Protein folding: energy landscapes and molecular dynamics
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Explores molecular glues as new drug modalities, focusing on binding forces, energetics, biomolecular interactions, quantification, drug development, and structural characterization.
Explores the conformational and functional flexibility of Hsp70 molecular chaperones, focusing on folding intermediates and the Hsp70 functional cycle.
Delves into the energetic determinants of protein folding, equilibrium constants, and thermodynamic properties of proteins, emphasizing enthalpy, entropy, and heat capacity.
