Selective Drug Targeting Mechanisms

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Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Altered Pathways in Cancer: Signaling Cascades and Mutations

Explores cancer pathways, major signaling cascades, and mutations in RAS and BRAF genes.

Small Molecule Drugs: Cardiovascular Diseases

Explores the molecular basis and treatment of cardiovascular diseases, focusing on atherosclerosis, hypertension, and drug therapies.

Drug Metabolism: Xenobiotics and Enzymes

Explores drug metabolism, focusing on xenobiotics, enzymes, biotransformation reactions, and factors affecting drug metabolism.

Drug Targets: Receptors, Enzymes, and Therapeutics

Explores drug targets, including receptors, enzymes, and therapeutics, covering pharmacodynamics, case studies on NSAIDs, diabetes, and drug toxicity.

Drug Targets: Ligand-Gated Ion Channels and Kinase-Linked Receptors

Explores drug targets like ligand-gated ion channels and kinase-linked receptors, discussing mechanisms of action, clinical uses, and insulin's physiological context.

Interrogating SAR in Medical Chemistry

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Drug-Induced Liver Injury (DILI): Mechanisms and Mitigation

Delves into Drug-Induced Liver Injury (DILI) mechanisms, metabolism, and mitigation strategies in drug development.