Selective Drug Targeting Mechanisms

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Mutations and Cancer: The Role of P53 and HPV

Covers mutations, the role of P53 in cancer, and HPV's impact on tumorigenesis.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

Immune Selection and Cancer Evolution

Delves into immune selection, cancer evolution, neoantigen quality, fitness cost, tumor heterogeneity, and evolutionary predictions.

Pharmacokinetic & Pharmacodynamic Studies

Discusses the importance of assessing PK/PD relationships in drug development and the use of multiple PD biomarkers.

Kidney-on-a-Chip Technologies

Covers the state-of-the-art kidney-on-chip technologies aiming to facilitate pharmaceutical research and eliminate animal testing.

Kinase Inhibitors: Types and Mechanisms

Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.

Interrogating SAR: Medicinal Chemistry

Covers medicinal chemistry basics, high-throughput screening, lead discovery milestones, and compound selectivity in drug optimization.

Protein-Protein Interaction Networks

Explores protein-protein interaction networks, binding importance, experimental approaches, drug target identification, and network construction.

Genomic Alterations in Cancer

Explores genetic and epigenetic changes in cancer, including mutations, chromosomal alterations, and high-throughput measurement methods.