This lecture covers Physical Vapor Deposition (PVD) techniques, including evaporation and sputtering, used for depositing thin films in nanofabrication. It explains the process of vaporizing materials from a source to solidify on a substrate, the importance of directional deposition, and issues like metal diffusion, stress in thin films, and contamination. The lift-off process for patterning materials without etching is also discussed, along with the challenges of achieving proper metal contact. Various methods such as reactive sputtering and lift-off techniques are explored, emphasizing the critical factors for successful deposition processes.