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This lecture discusses the challenges faced with hip implants, focusing on the limited success rates in certain clinical scenarios and the need for innovative approaches such as 'functionalizing' implants to control bone remodeling. Strategies to enhance the clinical outcome, implant design variations, and the impact of micromotions on bone remodeling are explored. The lecture also delves into the development of implants as drug delivery systems, aiming to improve stability and reduce side effects through localized drug release.