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Explores gene regulation mechanisms, including chromatin accessibility, DNA looping, and transcription factors' role in controlling cellular functions.
Explores RNA switches' design and applications in synthetic biology, focusing on nature-inspired regulatory RNA principles for creating new biomolecular components and networks.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Delves into retooling the genetic code by expanding it beyond the standard amino acids, with a focus on eukaryotic mRNA translation and site-specific incorporation in fruit fly models.
Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.