Cell Cycle Regulation: CDKs and Cyclins

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Description

This lecture covers the regulation of the cell cycle through Cyclin Dependent Kinases (CDKs) and cyclins. It explains how different CDKs and cyclins cooperate to control cell cycle progression, focusing on the roles of CDK1, CDK2, CDK4, and CDK6. The lecture details the functions of MPF (Mitosis Promoting Factor) and SPF (S-phase Promoting Factor) in driving cells through the cell cycle phases. It also discusses the importance of cyclin levels and CDK activity fluctuations during the cell cycle, emphasizing the significance of specific CDK/cyclin combinations in different cell cycle stages.

Instructors (4)

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Official source

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Ontological neighbourhood

Biology

Cell biology: Cell cycle

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