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Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Explores the genetic basis of Prader-Villy syndrome and its comparison with Angelman syndrome, emphasizing DNA methylation patterns and chromosomal abnormalities.
Explores Parkinson's disease, covering its history, challenges in diagnosis, available treatments, neuropathological changes, and impact on motor control.
Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Explores personalized medicine, genetic variability, and drug response, emphasizing tailoring treatments based on individual genetic and metabolic profiles.