Telomere Syndromes: Molecular Mechanisms and Disease Implications

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Covers protein design fundamentals, including secondary structures, amino acid propensity, loops, and computational methods.

Explores SERF-related proteins' functions in amyloid acceleration and G-quadruplex binding, shedding light on their complex mechanisms.

Protein Structure Determination

Explores protein structure determination using NMR and Cryo-EM techniques, covering chemical shifts, isotope labeling, NOE, and high-resolution imaging methods.

Immunoprecipitation: Isolating Proteins of Interest

Explains immunoprecipitation, isolating proteins using specific antibodies and solid supports.

Protein-protein Interaction Networks

Explores the importance and complexity of protein-protein interaction networks, experimental approaches, virus-host interactions, and network construction.

Synchrotrons and X-ray Techniques

Explores synchrotrons, X-ray techniques, crystallography, enzyme structures, mutant engineering, and the future of macromolecular crystallography.

Protein Co-evolution Analysis

Delves into protein co-evolution analysis, covering discoveries, residue contacts, and direct coupling analysis.

Protein Function Regulation: Degradation Mechanisms

Covers the mechanisms of protein degradation, including the roles of the proteasome and autophagy in regulating protein function.

Non-refoldability in E. coli Proteome

Delves into non-refoldability in the E. coli proteome, exploring protein folding challenges and implications.

Protein Structure and Function: Folding and Degradation

Covers protein folding, maturation, degradation, and the implications of misfolding in neurodegenerative diseases.