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Maxim Norkin

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Related units (1)

Prof. Huelsken Group

EPFL
SV
ISREC
UPHUELSKEN

Related publications (5)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

IFNγ-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy

Maxim Norkin, Angela Madurga Alonso, Jörg Hülsken, Laurent Nam Ky Beziaud

Despite the remarkable success of immune checkpoint blockade (ICB) therapy, most cancer patients still do not respond. We now find that immunotherapy can induce stem-like properties in tumors. Using mouse models of breast cancer, we observe that cancer ste ...

Elsevier BV2023

Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma

Maxim Norkin, Jörg Hülsken

Background We propose a new approach for designing personalized treatment for colorectal cancer (CRC) patients, by combining ex vivo organoid efficacy testing with mathematical modeling of the results. ...

BMC2023

Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes

Maxim Norkin, Jörg Hülsken, Paloma Ordonez Moran

The genomes of many human CRCs have been sequenced, revealing a large number of genetic alterations. However, the molecular mechanisms underlying the accumulation of these alterations are still being debated. In this study, we examined colorectal tumours t ...

2021