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Lucia Bonati

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Related publications (7)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Related units (2)

Laboratory of Protein Design & Immunoengineering

EPFL
STI
IBI-STI
LPDI

Laboratory of Biomaterials for Immunoengineering

EPFL
STI
IBI-STI
LBI

The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer

Li Tang, Lucia Bonati, Mei-Wen Peng, Rongrong Li, Yugang Guo, Yang Zhao, Bing Feng

Current cancer immunotherapy predominately focuses on eliciting type 1 immune responses fighting cancer; however, long-term complete remission remains uncommon1,2. A pivotal question arises as to whether type 2 immunity can be orchestrated alongside type 1 ...

2024

Rational cytokine and receptor engineering for enhanced safety and efficacy of cancer immunotherapy

The emergence of immunotherapy, including immune checkpoint blockade (ICB) and the adoptive transfer of cytotoxic lymphocytes, such as CAR-T cell therapy, has revolutionized cancer treatment. However, these therapies still face significant challenges in t ...

EPFL2025

Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases

Li Tang, Lucia Bonati

Disease progression is usually accompanied by changes in the biochemical composition of cells and tissues and their biophysical properties. For instance, hallmarks of cancer include the stiffening of tissues caused by extracellular matrix remodelling and t ...

Nature Portfolio2024