Unit
Laboratory of Biomaterials for Immunoengineering
LaboratorySummary
The Biomaterial Laboratory for Immunoengineering at EPFL, led by Dr. Li Tang, focuses on immunoengineering to develop safe and effective therapies against cancer and infectious diseases. Their research program includes reprogramming immune cell metabolism, achieving tissue-specific immune modulation, and manipulating mechanical properties for enhanced immunotherapy.
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Ontological neighbourhood
Related people (7)
Related publications (112)
Exploration and modulation of mechanical cues for enhanced cancer immunotherapy
The advent of immunotherapy, such as immune checkpoint blockade (ICB) and adoptive transfer of cytotoxic lymphocytes, has transformed the clinical care of cancer. However, a significant proportion of patients are resistant to immunotherapy or experience re ...
EPFL2024Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy
Dendritic cells (DCs) are specialized myeloid cells with the ability to uptake, process, andpresent antigens to T lymphocytes. They also generate cytokine and chemokine gradients thatregulate immune cell trafficking, activation, and function. Monocyte-deri ...
EPFL20246-diazo-5-oxo-l-norleucine prodrugs
Xile Hu, Li Tang, Céline Jasmin Prange
The present invention relates to 6-diazo-5-oxo-L-norleucine prodrugs having reduced toxicity and increased tumor specificity and to their therapeutic use for treating cancer. ...
2024