Sequence alignmentIn bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix. Gaps are inserted between the residues so that identical or similar characters are aligned in successive columns.
Hyperconnected spaceIn the mathematical field of topology, a hyperconnected space or irreducible space is a topological space X that cannot be written as the union of two proper closed sets (whether disjoint or non-disjoint). The name irreducible space is preferred in algebraic geometry. For a topological space X the following conditions are equivalent: No two nonempty open sets are disjoint. X cannot be written as the union of two proper closed sets. Every nonempty open set is dense in X. The interior of every proper closed set is empty.
Locally simply connected spaceIn mathematics, a locally simply connected space is a topological space that admits a basis of simply connected sets. Every locally simply connected space is also locally path-connected and locally connected. The circle is an example of a locally simply connected space which is not simply connected. The Hawaiian earring is a space which is neither locally simply connected nor simply connected. The cone on the Hawaiian earring is contractible and therefore simply connected, but still not locally simply connected.
Semi-locally simply connectedIn mathematics, specifically algebraic topology, semi-locally simply connected is a certain local connectedness condition that arises in the theory of covering spaces. Roughly speaking, a topological space X is semi-locally simply connected if there is a lower bound on the sizes of the “holes” in X. This condition is necessary for most of the theory of covering spaces, including the existence of a universal cover and the Galois correspondence between covering spaces and subgroups of the fundamental group.
Homotopical connectivityIn algebraic topology, homotopical connectivity is a property describing a topological space based on the dimension of its holes. In general, low homotopical connectivity indicates that the space has at least one low-dimensional hole. The concept of n-connectedness generalizes the concepts of path-connectedness and simple connectedness. An equivalent definition of homotopical connectivity is based on the homotopy groups of the space. A space is n-connected (or n-simple connected) if its first n homotopy groups are trivial.
Totally disconnected spaceIn topology and related branches of mathematics, a totally disconnected space is a topological space that has only singletons as connected subsets. In every topological space, the singletons (and, when it is considered connected, the empty set) are connected; in a totally disconnected space, these are the only connected subsets. An important example of a totally disconnected space is the Cantor set, which is homeomorphic to the set of p-adic integers. Another example, playing a key role in algebraic number theory, is the field Qp of p-adic numbers.
Completely metrizable spaceIn mathematics, a completely metrizable space (metrically topologically complete space) is a topological space (X, T) for which there exists at least one metric d on X such that (X, d) is a complete metric space and d induces the topology T. The term topologically complete space is employed by some authors as a synonym for completely metrizable space, but sometimes also used for other classes of topological spaces, like completely uniformizable spaces or Čech-complete spaces.
