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A comprehensive error rate for multiple testing

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Liquid metal infiltration of silicon based alloys into porous carbonaceous materials. Part I: Modelling of channel filling and reaction phase formation

Ludger Weber, Alberto Ortona, Manoj Kondibhau Naikade

A relation for an adequate pore fraction needed to obtain residual Si and C free composites via reactive Si-X alloy infiltration is presented. The volume ratio of SiC and carbonaceous phase, the composition of the infiltrating liquid and the apparent densi ...

ELSEVIER SCI LTD2022

Multiple testing with test statistics following heavy-tailed distributions

Zhiwen Jiang

In multiple testing problems where the components come from a mixture model of noise and true effect, we seek to first test for the existence of the non-zero components, and then identify the true alternatives under a fixed significance level

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. Two ...

EPFL2021

Genetically-encoded fluorescent sensors for neuromodulators are increasingly used molecular tools in neuroscience. However, these protein-based biosensors are often limited by the sensitivity of the protein scaffold towards endogenous ligands. Here, we exp ...

2021

Objectives To determine and compare the qualitative and quantitative diagnostic performance of a single sagittal fast spin echo (FSE) T2-weighted Dixon sequence in differentiating benign and malignant vertebral compression fractures (VCF), using multiple r ...

SPRINGER2021

Colloidal Synthesis of Cu-M-S (M = V, Cr, Mn) Nanocrystals by Tuning the Copper Precursor Reactivity

Raffaella Buonsanti, Seyedehbehnaz Varandili, James Richard Pankhurst, Valeria Mantella

New ternary and higher order inorganic materials are needed for a large variety of applications, yet their synthesis still represents a chemistry challenge. Herein, we focus on the synthesis of Cu-M-S nanocrystals (where M = V, Cr, Mn) via a wet-chemistry ...

AMER CHEMICAL SOC2020

Topological Fano Resonances

Romain Christophe Rémy Fleury, Farzad Zangeneh Nejad

The Fano resonance is a widespread wave scattering phenomenon associated with a peculiar asymmetric and ultrasharp line shape, which has found applications in a large variety of prominent optical devices. While its substantial sensitivity to geometrical an ...

2019

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Alessandro Angelini, Alessandro Zorzi, Sara Linciano

Peptides and small protein scaffolds are gaining increasing interest as therapeutics. Similarly to full-length antibodies, they can bind a target with a high binding affinity and specificity while remaining small enough to diffuse into tissues. However, de ...

ROYAL SOC CHEMISTRY2019

Ambiance in Social Media Venues: Visual Cue Interpretation by Machines and Crowds

Daniel Gatica-Perez, Gülcan Can, Yassir Benkhedda

We study the perception of ambiance of places captured in social media images by both machines and crowdworkers. This task is challenging due to the subjective nature of the ambiance construct as well as the large variety in layout, style, and visual chara ...

IEEE2018

Monobodies as possible next-generation protein therapeutics - a perspective

Over the past two decades, hundreds of new somatic mutations have been identified in tumours, and a few dozen novel cancer therapeutics that selectively target these mutated oncoproteins have entered clinical practice. This development has resulted in clin ...

2017

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This paper aims to describe and explain the processes behind the creation of a digital library composed of two Swiss newspapers, namely Gazette de Lausanne (1798-1998) and Journal de Genève (1826-1998), covering an almost two-century period. We developed a ...

2016

Multiple testing with test statistics following heavy-tailed distributions

Zhiwen Jiang

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. Two ...

EPFL2021