Bonferroni correctionIn statistics, the Bonferroni correction is a method to counteract the multiple comparisons problem. The method is named for its use of the Bonferroni inequalities. An extension of the method to confidence intervals was proposed by Olive Jean Dunn. Statistical hypothesis testing is based on rejecting the null hypothesis if the likelihood of the observed data under the null hypotheses is low. If multiple hypotheses are tested, the probability of observing a rare event increases, and therefore, the likelihood of incorrectly rejecting a null hypothesis (i.
Family-wise error rateIn statistics, family-wise error rate (FWER) is the probability of making one or more false discoveries, or type I errors when performing multiple hypotheses tests. John Tukey developed in 1953 the concept of a familywise error rate as the probability of making a Type I error among a specified group, or "family," of tests. Ryan (1959) proposed the related concept of an experimentwise error rate, which is the probability of making a Type I error in a given experiment.
False discovery rateIn statistics, the false discovery rate (FDR) is a method of conceptualizing the rate of type I errors in null hypothesis testing when conducting multiple comparisons. FDR-controlling procedures are designed to control the FDR, which is the expected proportion of "discoveries" (rejected null hypotheses) that are false (incorrect rejections of the null). Equivalently, the FDR is the expected ratio of the number of false positive classifications (false discoveries) to the total number of positive classifications (rejections of the null).
Energy conditionIn relativistic classical field theories of gravitation, particularly general relativity, an energy condition is a generalization of the statement "the energy density of a region of space cannot be negative" in a relativistically-phrased mathematical formulation. There are multiple possible alternative ways to express such a condition such that can be applied to the matter content of the theory. The hope is then that any reasonable matter theory will satisfy this condition or at least will preserve the condition if it is satisfied by the starting conditions.
Functional magnetic resonance imagingFunctional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990.
StatisticA statistic (singular) or sample statistic is any quantity computed from values in a sample which is considered for a statistical purpose. Statistical purposes include estimating a population parameter, describing a sample, or evaluating a hypothesis. The average (or mean) of sample values is a statistic. The term statistic is used both for the function and for the value of the function on a given sample. When a statistic is being used for a specific purpose, it may be referred to by a name indicating its purpose.
Congruence (general relativity)In general relativity, a congruence (more properly, a congruence of curves) is the set of integral curves of a (nowhere vanishing) vector field in a four-dimensional Lorentzian manifold which is interpreted physically as a model of spacetime. Often this manifold will be taken to be an exact or approximate solution to the Einstein field equation. Congruences generated by nowhere vanishing timelike, null, or spacelike vector fields are called timelike, null, or spacelike respectively.
NeuroimagingNeuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness. Neuroimaging is highly multidisciplinary involving neuroscience, computer science, psychology and statistics, and is not a medical specialty.
Causal structureIn mathematical physics, the causal structure of a Lorentzian manifold describes the causal relationships between points in the manifold. In modern physics (especially general relativity) spacetime is represented by a Lorentzian manifold. The causal relations between points in the manifold are interpreted as describing which events in spacetime can influence which other events. The causal structure of an arbitrary (possibly curved) Lorentzian manifold is made more complicated by the presence of curvature.
Cosmic censorship hypothesisThe weak and the strong cosmic censorship hypotheses are two mathematical conjectures about the structure of gravitational singularities arising in general relativity. Singularities that arise in the solutions of Einstein's equations are typically hidden within event horizons, and therefore cannot be observed from the rest of spacetime. Singularities that are not so hidden are called naked. The weak cosmic censorship hypothesis was conceived by Roger Penrose in 1969 and posits that no naked singularities exist in the universe.
