Publication
Neuromodulation/neurostimulation system for mitigating locomotor deficits of parkinson's disease, spinal cord injury (sci), stroke and/or other neurological disorders
Related publications (57)
Non-invasive neuromodulation of the right temporoparietal junction using theta-burst stimulation in functional neurological disorder
Background Disrupted sense of agency (SoA)-the sense of being the agent of one's own actions-has been demonstrated in patients with functional neurological disorder (FND), and a key area of the corresponding neuronal network is the right temporoparietal ju ...
London2024Non-invasive spinal cord electrical stimulation for arm and hand function in chronic tetraplegia: a safety and efficacy trial
Grégoire Courtine, Jordan Squair, Markus Maximilian Rieger
Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions. Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk trial that evaluated the safety and efficacy of ARCEX Therapy to improve a ...
Nature Portfolio2024System for control of spasticity
Grégoire Courtine, Jocelyne Bloch, Robin Jonathan Demesmaeker, Fabien Bertrand Paul Wagner, Karen Minassian, Salif Axel Komi
The present invention relates to a neuromodulation/neurostimulation system (10) for the treatment of spasticity in a mammal, said system (10) comprising: - at least one control unit (12) configured and arranged to provide stimulation data, and - at least o ...
2024Walking naturally after spinal cord injury using a brain-spine interface
Grégoire Courtine, Jocelyne Bloch, Léonie Asboth, Robin Jonathan Demesmaeker, Anne Marie Lucienne Watrin, Sergio Daniel Hernandez, Henri Charles Alexandre Lorach, Jimmy James Ravier, Grégory Didier Dumont, Félix Antoine Martel, Laure Coquoz, Valeria Spagnolo, Thibault Jean Etienne Collin, Icare Sakr, Lucas Struber, Salif Axel Komi, Molywan Vat, Carmina Andrea Galvez Solano, Edeny Baaklini, Cathal John Harte
A spinal cord injury interrupts the communication between the brain and the region of the spinal cord that produces walking, leading to paralysis(1,2). Here, we restored this communication with a digital bridge between the brain and spinal cord that enable ...
NATURE PORTFOLIO2023Sensory-Motor Neurostimulation to Enhance Exosuit Performance
Silvestro Micera, Andrea Crema, Stanisa Raspopovic, Giacomo Valle
Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...
New York2023Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury.
Spinal Cord Injury (SCI) affects almost 500,000 people every year, causing complete paralysis of both legs in severe cases, with no current treatment perspective. However, new neuroengineering technologies, such as the Brain Spine Interface (BSI), have eme ...
EPFL2023Closed-Loop Control of Epidural Electrical Stimulation in Patients with Spinal Cord Injury and Parkinson's Disease
Over the past two decades, epidural electrical stimulation (EES) has transitioned from a treatment for chronic pain to a promising paradigm for ameliorating deficits associated with neurological disorders like spinal cord injury (SCI) and Parkinson's Disea ...
EPFL2023A digital bridge between brain and spinal cord restores walking after paralysis
Grégoire Courtine, Jocelyne Bloch
Spinal-cord injury interrupts communication between the brain and spinal cord, leading to paralysis. An implant that decodes the brain signals that control movements and drives electrical stimulation of the spinal cord re-establishes this communication, en ...
NATURE PORTFOLIO2023Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders
Spinal Cord Injury (SCI) disrupts the communication between the brain and spinal circuits below the lesion, leading to a plethora of neurological impairments, including the loss of motor function. At present, the only medical practices to enhance recovery ...
EPFL2021Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders
Neurological disorders such as spinal cord injury (SCI) massively reduce independence and quality of life. Most often, the majority of the nervous system is still fully or partially spared, but dysfunctional due to aberrant or absent descending input from ...
EPFL2021