High-throughput screeningHigh-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology, materials science and chemistry. Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly conduct millions of chemical, genetic, or pharmacological tests. Through this process one can quickly recognize active compounds, antibodies, or genes that modulate a particular biomolecular pathway.
Weyl semimetalWeyl fermions are massless chiral fermions embodying the mathematical concept of a Weyl spinor. Weyl spinors in turn play an important role in quantum field theory and the Standard Model, where they are a building block for fermions in quantum field theory. Weyl spinors are a solution to the Dirac equation derived by Hermann Weyl, called the Weyl equation. For example, one-half of a charged Dirac fermion of a definite chirality is a Weyl fermion. Weyl fermions may be realized as emergent quasiparticles in a low-energy condensed matter system.
High-content screeningHigh-content screening (HCS), also known as high-content analysis (HCA) or cellomics, is a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner. Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or components of cells with simultaneous readout of several parameters.
Topological insulatorA topological insulator is a material whose interior behaves as an electrical insulator while its surface behaves as an electrical conductor, meaning that electrons can only move along the surface of the material. A topological insulator is an insulator for the same reason a "trivial" (ordinary) insulator is: there exists an energy gap between the valence and conduction bands of the material. But in a topological insulator, these bands are, in an informal sense, "twisted", relative to a trivial insulator.
Weyl equationIn physics, particularly in quantum field theory, the Weyl equation is a relativistic wave equation for describing massless spin-1/2 particles called Weyl fermions. The equation is named after Hermann Weyl. The Weyl fermions are one of the three possible types of elementary fermions, the other two being the Dirac and the Majorana fermions. None of the elementary particles in the Standard Model are Weyl fermions. Previous to the confirmation of the neutrino oscillations, it was considered possible that the neutrino might be a Weyl fermion (it is now expected to be either a Dirac or a Majorana fermion).
Topological orderIn physics, topological order is a kind of order in the zero-temperature phase of matter (also known as quantum matter). Macroscopically, topological order is defined and described by robust ground state degeneracy and quantized non-Abelian geometric phases of degenerate ground states. Microscopically, topological orders correspond to patterns of long-range quantum entanglement. States with different topological orders (or different patterns of long range entanglements) cannot change into each other without a phase transition.
Topological propertyIn topology and related areas of mathematics, a topological property or topological invariant is a property of a topological space that is invariant under homeomorphisms. Alternatively, a topological property is a proper class of topological spaces which is closed under homeomorphisms. That is, a property of spaces is a topological property if whenever a space X possesses that property every space homeomorphic to X possesses that property. Informally, a topological property is a property of the space that can be expressed using open sets.
Electronic band structureIn solid-state physics, the electronic band structure (or simply band structure) of a solid describes the range of energy levels that electrons may have within it, as well as the ranges of energy that they may not have (called band gaps or forbidden bands). Band theory derives these bands and band gaps by examining the allowed quantum mechanical wave functions for an electron in a large, periodic lattice of atoms or molecules.
Topological spaceIn mathematics, a topological space is, roughly speaking, a geometrical space in which closeness is defined but cannot necessarily be measured by a numeric distance. More specifically, a topological space is a set whose elements are called points, along with an additional structure called a topology, which can be defined as a set of neighbourhoods for each point that satisfy some axioms formalizing the concept of closeness.
Topological groupIn mathematics, topological groups are logically the combination of groups and topological spaces, i.e. they are groups and topological spaces at the same time, such that the continuity condition for the group operations connects these two structures together and consequently they are not independent from each other. Topological groups have been studied extensively in the period of 1925 to 1940. Haar and Weil (respectively in 1933 and 1940) showed that the integrals and Fourier series are special cases of a very wide class of topological groups.