A roadmap for the development of precision medicine

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Climatic Affinities or Type As A Structure Of Relations Based On Typological Transfer In The Work Of Lacaton & Vassal And Other Similar Precedents

It is a generally accepted idea that typology is an essential element in the disciplinary dimension of architecture. The concept of typology, in its most common definition, is sufficiently malleable to cover a wide range of uses, but it is also this vaguen ...

2023

The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma

Paul Joseph Dyson, Irina Sinenko, Roland Christopher Turnell-Ritson

Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improv ...

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2023

Methodology for selecting measurement points that optimize information gain for model updating

Ian Smith, Numa Joy Bertola

Information collected through sensor measurements has the potential to improve knowledge of complex-system behavior, leading to better decisions related to system management. In this situation, and particularly when using digital twins, the quality of sens ...

2023

Roadmap on Machine learning in electronic structure

Michele Ceriotti, Jigyasa Nigam, Andrea Grisafi, Max David Veit

In recent years, we have been witnessing a paradigm shift in computational materials science. In fact, traditional methods, mostly developed in the second half of the XXth century, are being complemented, extended, and sometimes even completely replaced by ...

IOP Publishing Ltd2022

Towards Beam-Beam Simulations for FCC-ee

Tatiana Pieloni, Xavier Buffat, Mike Seidel, Giovanni Iadarola, Péter Kicsiny

The FCC-ee (Future Circular Collider) lepton collider is currently the most favored next generation research infrastructure project at CERN, aimed at studying properties of standard model particles with the highest precision ever. The chosen parameters of ...

JACoW Publishing, Geneva, Switzerland2022

On the development of multi-physics tools for nuclear reactor analysis based on OpenFOAM (R): state of the art, lessons learned and perspectives

Carlo Fiorina

In the last two decades, the use of OpenFOAM as a multi-physics library for nuclear applications has grown from a sporadic use for exploratory studies to a widespread application for the analysis of innovative reactor concepts and highly complex problems. ...

ELSEVIER SCIENCE SA2022

UAV in the advent of the twenties: Where we stand and what is next

Jan Skaloud, Davide Antonio Cucci

The use of Unmanned Aerial Vehicles (UAVs) has surged in the last two decades, making them popular instruments for a wide range of applications, and leading to a remarkable number of scientific contributions in geoscience, remote sensing and engineering. H ...

2022

Exploring Photoredox-Catalyzed (Re)functionalizations with Core-Modified Benziodoxolones

Jérôme Waser, Franck Le Vaillant, Stephanie Grace Elizabeth Amos

Alkynes and nitriles are valuable building blocks in organic synthesis and also have multiple applications in chemical biology and materials science. Due to the high availability of tertiary alcohols, developing methods for their conversion into alkynes an ...

2022

Material Development for Perovskite/Silicon Tandem Photovoltaics

Peter Joseph Fiala

The developed world is built on the fact that energy is readily available and functionally infinite. The electricity from the wall, the gas at the station, and the heat in our homes are reliable and low-cost. But this comfort is so far only possible throug ...

EPFL2022

Assessing Computational Thinking: Development and Validation of the Algorithmic Thinking Test for Adults

Olivier Lévêque, Cécile Hardebolle, Jessica Elke Dehler Zufferey, Marc Lafuente Martinez

This study describes the development and validation process of a computational thinking (CT) test for adults. The team designed a set of items and explored a subset of those through two qualitative pilots. Then, in order to provide validity evidence based ...

2022

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Climatic Affinities or Type As A Structure Of Relations Based On Typological Transfer In The Work Of Lacaton & Vassal And Other Similar Precedents

Tiago André Pratas Borges

2023

On the development of multi-physics tools for nuclear reactor analysis based on OpenFOAM (R): state of the art, lessons learned and perspectives

Carlo Fiorina

ELSEVIER SCIENCE SA2022