Publications related to Implantable blood pressure monitor

Novel theory and potential applications of central diastolic pressure decay time constant

Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia, Patrick Segers

Central aortic diastolic pressure decay time constant ( ) is according to the two-element Windkessel model equal to the product of total peripheral resistance (R) times total arterial compliance (C ). As such, it is related to arterial stiffness, which has ...

2024

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

Nature Portfolio2023

Modulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction

Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou

Background:Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hype ...

Lippincott Williams & Wilkins2023

Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet

Vasiliki Bikia, Patrick Segers

Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review th ...

AMER PHYSIOLOGICAL SOC2023

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy

Nikolaos Stergiopoulos, Augusto Martins Lima, Valeria Romina Martinez

Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used for hypertension treatment. Structural modifications were previously perf ...

ELSEVIER2023

Data-driven approaches for non-invasive cuffless blood pressure monitoring

Clémentine Léa Aguet

Blood pressure (BP) is a crucial indicator of cardiovascular health. Hypertension is a common life-threatening condition and a key factor of cardiovascular diseases (CVDs). Identifying abnormal BP fluctuations can allow for early detection and management o ...

EPFL2023

Compliance-matching vascular grafts with personalization potential

Georgios Rovas

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

EPFL2023

Fiber pumps for wearable fluidic systems

Herbert Shea, Michael James Henry Smith, Vito Cacucciolo

Incorporating pressurized fluidic circuits into textiles can enable muscular support, thermoregulation, and haptic feedback in a convenient wearable form factor. However, conventional rigid pumps, with their associated noise and vibration, are unsuitable f ...

American Association for the Advancement of Science2023

Integrated Electronics for Deep Implants to Remotely Monitor Hemodynamics

Mustafa Besirli

The integration of technology in the medical field has greatly improved accuracy in diagnoses, thus leading to more effective treatments. Wearable and implantable medical devices offer great potential for remote patient monitoring, particularly for heart f ...

EPFL2023

Longitudinal interrogation of sympathetic neural circuits and hemodynamics in preclinical models

Grégoire Courtine, Quentin Barraud, Jordan Squair, Matthieu Pierre Gautier, Victor Perez Puchalt, Loïs Thomas Romain Mahe, Rémi Bernard René Hudelle, Jan Elaine Cuevas Soriano, Suje Amir

Neurological disorders, including spinal cord injury, result in hemodynamic instability due to the disruption of supraspinal projections to the sympathetic circuits located in the spinal cord. We recently developed a preclinical model that allows the ident ...

NATURE PORTFOLIO2022