Rapid Production of Submicron Drug Substance Particles by Supersonic Spray Drying

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Related publications (22)

Characterization of the Flow Generated in an Annular Test Facility

Peter Ott, Elia Colombo, Dominique Charbonnier, Cécile Deslot

Annular cascades are particularly useful to study the three dimensional phenomena encountered in turbomachines. The Non-Rotating Annular Test Facility of the Swiss Federal Institute of Technology in Lausanne (EPFL) consists in a radial-axial inlet nozzle a ...

2011

Investigation on the Three-Dimensional Flow Mechanisms in Annular Axial Compressor Cascades for Aero Engines with Flow Control by Aspiration on the Hub and on the Blades

Elia Colombo

The axial compressor is an essential component of aero-engines and gas turbines. This work investigates how flow control by aspiration applied to the hub and to the blades of axial compressor wheels can improve the static pressure rise by preventing detrim ...

EPFL2011

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

Martinus Gijs, Caroline Vandevyver, Venkataragavalu Sivagnanam

We propose an original concept for a sandwich immunoassay that is completely performed on-chip using streptavidin-coated beads as substrate. The latter are electrostatically self-assembled on aminosilane micropatterns at the bottom of a microfluidic channe ...

2009

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

Martinus Gijs, Caroline Vandevyver, Venkataragavalu Sivagnanam, Hui Yang, Bo Song

2009

Interaction between a surface dielectric barrier discharge and transonic airflows

Samantha Pavon

The use of plasmas in aerodynamics has become a recent topic of interest. The potentialities of different types of plasmas are being investigated for low velocity and high velocity flow control, as well as for plasma-assisted combustion. Dielectric barrier ...

EPFL2008

The gas flow rate increase obtained by an oscillating piezoelectric actuator on a micronozzle

Jürgen Brugger

Micronozzles with piezoelectric actuator were fabricated and investigated. The micronozzles were fabricated in glass substrates using a powderblasting technique, and the actuator is a bimorph structure made from a piezoelectric polymer. The actuator was lo ...

2008

Numerical and experimental investigation of the shock-vane interaction in a transonic compressor

Stefan Kristukat

A numerical and experimental investigation of the shock-IGV (inlet guide vane) interaction in a transonic compressor is conducted at the Laboratoire de Thermique Appliquée et de Turbomachines (LTT) at the Ecole Polytechnique Fédérale de Lausanne (EPFL). Th ...

EPFL2008

Hydrodynamics of the free surface flow in Pelton turbine buckets

Alexandre Perrig

The design of Pelton turbines has always been more difficult than that of reaction turbines, and their performances lower. Indeed, the Pelton turbines combine 4 types of flows: (i) confined, steady-state flow in the piping systems and injector, (ii) free w ...

EPFL2007

Effects of high-speed airflows on a surface dielectric barrier discharge

Christoph Hollenstein, Peter Ott, Pénélope Leyland, Samantha Pavon

A detailed study of the interaction between high-speed gas flows and surface dielectric barrier discharges (DBD) is presented. In the present paper, it is demonstrated that a DBD can be sustained in transonic airflows, up to isentropic Mach numbers of 1.1. ...

2007

Inclusion of aerodynamic non-equilibrium effects in supersonic plasma jet enthalpy probe measurements

Christoph Hollenstein, Malko Gindrat

Low pressure plasma spraying (LPPS) is a thermal spraying technique that has found a niche for low oxidation products. It uses a low pressure environment (i.e:, chamber pressure between 2 and 90 kPa) and yields supersonic plasma jets. The enthalpy probe te ...

2005

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Investigation on the Three-Dimensional Flow Mechanisms in Annular Axial Compressor Cascades for Aero Engines with Flow Control by Aspiration on the Hub and on the Blades

Elia Colombo

EPFL2011