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The Integrated Systems Laboratory (LSI) at EPFL focuses on design technologies for circuits and systems, exploring the interplay of hardware and software design for traditional and non-traditional systems. Research areas include design technologies for nanosystems, system-level optimization, and the use of new circuit technologies like superconducting circuits and nanotechnologies. Recent achievements include winning prestigious awards for papers on logic synthesis for garbled circuits and synthesis of superconductive logic networks in SFQ technology.