Publications associées à Abus de substances

Charge-Selectively Permeable Self-Healing Microcapsules

Microcapsules possessing a selective permeability are well-suited vessels for conducting cell studies or chemical reactions that require selective exchanges of reagents over a prolonged time. Most currently reported microcapsules are single-use delivery ca ...

WILEY2023

Selectively permeable microcapsules

Chuen-Ru Li

Microcapsules are appealing containers for delivering active ingredients, such as drugs and cosmetics, or conducting chemical and biological reactions on a small scale. To control the timing and location of release of these encapsulants, the shells of micr ...

EPFL2023

Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets

Christoph Merten, Ngoc Hien Du

Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that might be tackled with drug combinations. Identification of the right combination is challenging and would benefit from high-content, ...

Nature Research2022

Repurposed drug combination via high-throughput screening and dual drug delivery system development for the treatment of retinoblastoma

Po-Jen Tseng

The goal of retinoblastoma (RB) treatment is to save the child's life, eyes and functional vision, with that order of priority. The management of RB is complex and involves strategically chosen methods of surgical enucleation, external beam radiotherapy, i ...

EPFL2022

Lieu hologrammatique, un concept et une méthodologie complexe de mesure de l'organisation spatiale des réalités sociales

Thibault Pierre Louis Romany

The urban is a complex phenomenon whose exploration remains a important scientific challenge. Choosing complex thought in order to renew our capacities for understanding and action on and with the urban is not trivial. The complex thought developed by Edga ...

EPFL2020

Re-entry survival analysis and ground risk assessment of space debris considering by-products generation

Pénélope Leyland, Stefano Mischler, Seong-Hyeon Park

Space debris that re-enter the Earth's atmosphere can be partially or fully ablated along the trajectory path after hitting the atmosphere layers, once these become denser (approximately below 82 km). This paper combines re-entry survival analysis to by-pr ...

2020

A novel psychoanalytical approach: An electrochemical ligand-binding assay to screen antipsychotics

Sandro Carrara, Tugba Kilic

Schizophrenia treatment may see a paradigm shift due to development of new atypical antipsychotic drugs (APDs), with better tolerability due to more selective dopamine (DA) receptor blockade. Monitoring of these APD candidates in biological fluids is of gr ...

2018

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Nima Aliakbarinodehi, Sandro Carrara, Francesca Stradolini, Irene Taurino, Ioulia Tzouvadaki, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

Impact Assessment of Pesticides Applied in Vegetable-Producing Areas in the Saharan Zone : the Case of Burkina Faso

Edouard René Gilbert Lehmann

The present thesis aimed at characterizing the extent of the pesticide contamination and resulting impacts on the environment and the human health in market garden-ing areas in Burkina Faso. Analytical procedures were developed and validated for multi-clas ...

EPFL2017

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia

Erika Myrna Borcel Novoa

Although cocaine abuse is up to three times more frequent among schizophrenic patients, it remains unclear why this should be the case and whether sex influences this relationship. Using a maternal immune activation model of schizophrenia, we tested whethe ...

Pergamon-Elsevier Science Ltd2016