Concept

Épilepsie

Publications associées (103)

All Wireless, 16-channel Epilepsy Control System with Sub-mu W/channel and Closed-loop Stimulation Using a Switched-Capacitor-Based Active Charge Balancing Method

Alexandre Schmid, Catherine Dehollain, Kerim Türe, Reza Ranjandish, Franco Maloberti

An all wireless closed-loop stimulation system for epilepsy control is presented that generates charged-balanced programmable stimulation current pulses upon a seizure is detected. The proposed system has highly flexible stimulation parameters thanks to th ...

IEEE2018

Closed-loop electrical neurostimulation: Challenges and opportunities

José del Rocio Millán Ruiz, Inaki Asier Iturrate Gil, Michael Eric Anthony Pereira

Non-invasive and invasive electrical neurostimulation are promising tools to better understand brain function and ultimately treat its malfunction. In current open-loop approaches, a clinician chooses a fixed set of stimulation parameters, informed by obse ...

2018

A somatotopic bidirectional hand prosthesis with transcutaneous electrical nerve stimulation based sensory feedback

Silvestro Micera, Stanisa Raspopovic, Fiorenzo Artoni, Francesco Maria Petrini

According to amputees, sensory feedback is amongst the most important features lacking from commercial prostheses. Although restoration of touch by means of implantable neural interfaces has been achieved, these approaches require surgical interventions, a ...

2017

Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks

Silvestro Micera

Epilepsy is characterized by impaired circuit function and a propensity for spontaneous seizures, but how plastic rearrangements within the epileptic focus trigger cortical dysfunction and hyperexcitability is only partly understood. Here we have examined ...

Springer Heidelberg2016

Patient MoCap: Human Pose Estimation under Blanket Occlusion for Hospital Monitoring Applications

Alexandru Eugen Ichim, Huseyin Coskun

Motion analysis is typically used for a range of diagnostic procedures in the hospital. While automatic pose estimation from RGB-D input has entered the hospital in the domain of rehabilitation medicine and gait analysis, no such method is available for be ...

2016

Bidirectional Limb Neuro-Prosthesis

Silvestro Micera, Marco Capogrosso, Stanisa Raspopovic, Francesco Maria Petrini, Marco Bonizzato

Integrated closed-loop real-time limb neuro-prosthetic system comprising an artificial limb, a microprocessor, sensors, a signal conditioner, a stimulator, at least one EMG electrode and at least one sensory feedback electrode, characterized by the fact th ...

2016

Low-Power Circuit and System Design for Epileptic Seizure Detection at High Spatiotemporal Resolution

Mahsa Shoaran

Smart and miniaturized implantable microsystems with diagnostic and therapeutic capabilities are becoming increasingly important for patients suffering from neurological disorders such as epilepsy. Recent developments in microfabrication technology have pr ...

EPFL2015

Neural generators of psychogenic seizures: Evidence from intracranial and extracranial brain recordings

Olaf Blanke, Pär Halje

Psychogenic seizures (PSs) convincingly mimic seizure phenomena but with no underlying epileptic activity. However, not much is known about their neurophysiological basis. We had the rare opportunity to analyze intracranial brain recordings of PSs occurrin ...

2014

Connectivity and tissue microstructural alterations in right and left temporal lobe epilepsy revealed by diffusion spectrum imaging

Jean-Philippe Thiran, Alessandro Daducci, Nicolas Kunz, Alia Lemkaddem, François Lazeyras

Focal epilepsy is increasingly recognized as the result of an altered brain network, both on the structural and functional levels and the characterization of these widespread brain alterations is crucial for our understanding of the clinical manifestation ...

2014

Optimal Control of Transient Dynamics in Balanced Networks Supports Generation of Complex Movements

Wulfram Gerstner, Tim Vogels, Guillaume Hennequin

Populations of neurons in motor cortex engage in complex transient dynamics of large amplitude during the execution of limb movements. Traditional network models with stochastically assigned synapses cannot reproduce this behavior. Here we introduce a clas ...

Cell Press2014

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