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The recent availability of large corpora of digitized texts over several centuries opens the way to new forms of studies on the evolution of languages. In this thesis, we study a corpus of 4 million press articles covering a period of 200 years. The thesis ...
The participants in randomized trials and other studies used for causal inference are often not representative of the populations seen by clinical decision-makers. To account for differences between populations, researchers may consider standardizing resul ...
Covariance operators play a fundamental role in functional data analysis, providing the canonical means to analyse functional variation via the celebrated Karhunen-Loève expansion. These operators may themselves be subject to variation, for instance in con ...
Background. Muscle synergy analysis is an approach to understand the neurophysiological mechanisms behind the hypothesized ability of the Central Nervous System (CNS) to reduce the dimensionality of muscle control. The muscle synergy approach is also used ...
Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-conventional MR se ...
Susceptibility to obesity in today′s environment has a strong genetic component. Lower socioeconomic position (SEP) is associated with a higher risk of obesity but it is not known if it accentuates genetic susceptibility to obesity. We aimed to use up to 1 ...
Background: Previous studies have suggested that modern obesogenic environments accentuate the genetic risk of obesity. However, these studies have proven controversial as to which, if any, measures of the environment accentuate genetic susceptibility to h ...
Computing statistical measures for large databases of time series is a fundamental primitive for querying and mining time-series data [1]–[6]. This primitive is gaining importance with the increasing number and rapid growth of time series databases. In thi ...
We study the issue of localization in the context of isotropic wavelet frames. We define a variance-type measure of localization and propose an algorithm based on calculus of variations to minimize this criterion under the constraint of a tight wavelet fra ...
The discrete cosine transform (DCT) is known to be asymptotically equivalent to the Karhunen-Loève transform (KLT) of Gaussian first-order auto-regressive (AR(1)) processes. Since being uncorrelated under the Gaussian hypothesis is synonymous with independ ...