Publications associées à Test ADN généalogique

Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria

Although free-living and obligate intracellular bacteria are both polarized it is unclear whether the underlying polarization mechanisms and effector proteins are conserved. Here we dissect at the cytological, functional and structural level a conserved po ...

Elife Sciences Publications Ltd2016

Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models

Vassily Hatzimanikatis, Bart Deplancke, Alina Isakova, Yves Berset

Many transcription factors (TFs) have the ability to cooperate on DNA elements as heterodimers. Despite the significance of TF heterodimerization for gene regulation, a quantitative understanding of cooperativity between various TF dimer partners and its i ...

American Society for Biochemistry and Molecular Biology2016

Privacy-preserving genomic testing in the clinic: a model using HIV treatment

Jean-Pierre Hubaux, Jacques Fellay, Amalio Telenti, Erman Ayday, Jean Louis Raisaro, Istvan Bartha

The implementation of genomic-based medicine is hindered by unresolved questions regarding data privacy and delivery of interpreted results to health-care practitioners. We used DNA-based prediction of HIV-related outcomes as a model to explore critical is ...

Nature Publishing Group2016

SNP2TFBS - a database of regulatory SNPs affecting predicted transcription factor binding site affinity

Giovanna Ambrosini, Philipp Bucher, Sunil Kumar

SNP2TFBS is a computational resource intended to support researchers investigating the molecular mechanisms underlying regulatory variation in the human genome. The database essentially consists of a collection of text files providing specific annotations ...

Oxford University Press2016

Privacy in the Genomic Era

Jean-Pierre Hubaux, Jacques Fellay, Erman Ayday

Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highlydetailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including personalized medical ...

Assoc Computing Machinery2015

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak

Due to the helical structure of DNA the process of DNA replication is topologically complex. Freshly replicated DNA molecules are catenated with each other and are frequently knotted. For proper functioning of DNA it is necessary to remove all of these ent ...

Oxford University Press2015

Reconciling Utility with Privacy in Genomics

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday

Direct-to-consumer genetic testing makes it possible for everyone to learn their genome sequences. In order to contribute to medical research, a growing number of people publish their genomic data on the Web, sometimes under their real identities. However, ...

2014

Reconciling Utility with Privacy in Genomics

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday

2014

Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine

Jean-Pierre Hubaux, Jacques Rougemont, Erman Ayday, Jean Louis Raisaro

In this paper, we propose privacy-enhancing technologies for medical tests and personalized medicine methods that use patients' genomic data. Focusing on genetic disease-susceptibility tests, we develop a new architecture (between the patient and the medic ...

2013

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Test ADN généalogique

Coalescent inferences in conservation genetics: should the exception become the rule?

Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria

Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models

Privacy-preserving genomic testing in the clinic: a model using HIV treatment

SNP2TFBS - a database of regulatory SNPs affecting predicted transcription factor binding site affinity

Privacy in the Genomic Era

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

Reconciling Utility with Privacy in Genomics

Reconciling Utility with Privacy in Genomics

Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine

Graph Chatbot

Chattez avec Graph Search

Privacy in the Genomic Era

Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria

Privacy-preserving genomic testing in the clinic: a model using HIV treatment

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

SNP2TFBS - a database of regulatory SNPs affecting predicted transcription factor binding site affinity

Reconciling Utility with Privacy in Genomics

Reconciling Utility with Privacy in Genomics

Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine

Coalescent inferences in conservation genetics: should the exception become the rule?

Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models