Publications associées à Hippocampal sclerosis

Community-based reconstruction and simulation of a full-scale model of region CA1 of rat hippocampus

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, James Gonzalo King, Lida Kanari, Ying Shi, Armando Romani, Davide Bella, Felix Schürmann

The CA1 region of the hippocampus is one of the most studied regions of the rodent brain, thought to play an important role in cognitive functions such as memory and spatial navigation. Despite a wealth of experimental data on its structure and function, i ...

2024

Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs

Ying Shi, Armando Romani, Maurizio Ferdinando Pezzoli, Michele Migliore, Rosanna Migliore

The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into individual output spikes. These spikes, in turn, act as inputs for other neurons in the network. Neurons must execute this function acro ...

2023

Structure-function coupling increases during interictal spikes in temporal lobe epilepsy: A graph signal processing study

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Patric Hagmann

Objective: Structure-function coupling remains largely unknown in brain disorders. We studied this coupling during interictal epileptic discharges (IEDs), using graph signal processing in temporal lobe epilepsy (TLE). ...

ELSEVIER IRELAND LTD2023

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Elenor Morgenroth

Childhood trauma (CT) has been linked to increased risk for psychosis. Moreover, CT has been linked to psychosis phenotypes such as impaired cognitive and sensory functions involved in the detection of novel sensory stimuli. Our objective was to investigat ...

SPRINGER HEIDELBERG2023

EEG Spatiotemporal Patterns Underlying Self-other Voice Discrimination

Olaf Blanke, Pavo Orepic, Sixto Luis Alcoba Banqueri, Giannina Rita Iannotti, Thomas Koenig

There is growing evidence showing that the representation of the human “self” recruits special systems across different functions and modalities. Compared to self-face and self-body representations, few studies have investigated neural underpinnings specif ...

2021

When shared concept cells support associations: Theory of overlapping memory engrams

Wulfram Gerstner, Emanuela De Falco, Tilo Schwalger, Chiara Gastaldi

Assemblies of neurons, called concepts cells, encode acquired concepts in human Medial Temporal Lobe. Those concept cells that are shared between two assemblies have been hypothesized to encode associations between concepts. Here we test this hypothesis in ...

2021

OpenPifPaf: Composite Fields for Semantic Keypoint Detection and Spatio-Temporal Association

Alexandre Massoud Alahi, Sven Kreiss, Lorenzo Bertoni

Many image-based perception tasks can be formulated as detecting, associating and tracking semantic keypoints, e.g., human body pose estimation and tracking. In this work, we present a general framework that jointly detects and forms spatio-temporal keypoi ...

IEEE Institute of Electrical and Electronics Engineers2022

Remodeling of brain morphology in temporal lobe epilepsy

Bogdan Draganski, Lester Melie Garcia

Background Mesial temporal lobe epilepsy (TLE) is one of the most widespread neurological network disorders. Computational anatomy MRI studies demonstrate a robust pattern of cortical volume loss. Most statistical analyses provide information about localiz ...

2020

Hippocampal Contribution to Ordinal Psychological Time in the Human Brain

Baptiste Gauthier

The chronology of events in time-space is naturally available to the senses, and the spatial and temporal dimensions of events entangle in episodic memory when navigating the real world. The mapping of time-space during navigation in both animals and human ...

MIT PRESS2020

Depersonalization- and derealization-like phenomena of epileptic origin

Olaf Blanke, Lukas Heydrich, Nathaniel Evans

Objective Depersonalization refers to the sensation of being detached from one's body, often associated with feelings of loss of control over one's own body, actions, or thoughts. Derealization refers to the altered perception of one's surroundings that is ...

2019