Concept
Tissu nerveux
Publications associées (237)
Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization
Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...
EPFL2024Small-scale robotic devices for medical interventions in the brain
Mahmut Selman Sakar, Lorenzo Francesco John Noseda
This article summarizes the recent advancements in the design, fabrication, and control of microrobotic devices for the diagnosis and treatment of brain disorders. With a focus on diverse actuation methods, we discuss how advancements in materials science ...
2024Organ Neuroprosthetics: Connecting Transplanted and Artificial Organs with the Nervous System
Implantable neural interfaces with the central and peripheral nervous systems are currently used to restore sensory, motor, and cognitive functions in disabled people with very promising results. They have also been used to modulate autonomic activities to ...
Wiley2024Soft bioelectronic technologies for selective and multimodal peripheral nerve interfaces
The peripheral nervous system (PNS) regulates the exchange of sensory information andmotor commands between the body and the central nervous system. Further, through theautonomic nervous system, the PNS plays a pivotal role in controlling vital physiologic ...
EPFL2023Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function
Gioele La Manno, Zahra Moslehi, Nina-Lydia Kazakou
The myelinated white matter tracts of the central nervous system (CNS) are essential for fast transmission of electrical impulses and are often differentially affected in human neurodegenerative diseases across CNS region, age and sex. We hypothesize that ...
BMC2023Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain
Stéphanie Lacour, John Martin Kolinski, Outman Akouissi, Olivier Didier Christian Rizzo, Michael Shur
The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable format. We propose a simple fabrication and processing sequence, consisting of de-hydration, patte ...
2023Development of next-generation microfluidic systems for enhanced, faster, and cost-effective immunoassays for tissue diagnostics - Ac electrothermal flow & Acoustofluidics
The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...
EPFL2023Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution
Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a single-nucleus transcriptomic map of the whole aging Drosophila. We c ...
AMER ASSOC ADVANCEMENT SCIENCE2023