Traitement de l'information

Le traitement de l'information est le processus de changement de l'information de toute manière détectable par un observateur. Comme tel, c'est un processus qui décrit toutes les choses qui arrivent (changement) dans l'univers, depuis la chute d'une pierre (un changement de position) jusqu'à l'impression d'un texte à partir d'un système informatique numérique. Dans ce dernier cas, un système de traitement de l'information (ordinateur) change la forme de la présentation de ce fichier texte. Le traitement de l'information peut plus spécifiquement être défini en termes par Claude E. Shannon comme la conversion d'information latente en information manifeste. L'information latente ou manifeste est définie à travers les termes d'« équivocation » (incertitude résiduelle, quelle valeur a choisi l'émetteur), la dissipation (incertitude de l'émetteur sur ce que le récepteur a effectivement reçu) et transformation (effort économisé dans le questionnement – équivocation moins dissipation). En p

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Psychologie cognitive

La psychologie cognitive, ou psychologie de la connaissance, étudie les grandes fonctions psychologiques de l'être humain que sont la mémoire, le langage, l'intelligence, le raisonnement, la résolut

Mémoire (psychologie)

thumb|350px|Les formes et fonctions de la mémoire en sciences. En psychologie, la mémoire est la faculté de l'esprit d'enregistrer, conserver et rappeler les expériences passées. Son investigation es

Information

vignette|redresse=0.6|Pictogramme représentant une information. L’information est un de la discipline des sciences de l'information et de la communication (SIC). Au sens étymologique, l'« informatio

The EBRAINS Hodgkin-Huxley Neuron Builder: An online resource for building data-driven neuron models

Shailesh Appukuttan, Luca Leonardo Bologna, Jean-Denis Georges Emile Courcol, Genrich Ivaska, Carmen Alina Lupascu, Michele Migliore

In the last decades, brain modeling has been established as a fundamental tool for understanding neural mechanisms and information processing in individual cells and circuits at different scales of observation. Building data-driven brain models requires the availability of experimental data and analysis tools as well as neural simulation environments and, often, large scale computing facilities. All these components are rarely found in a comprehensive framework and usually require ad hoc programming. To address this, we developed the EBRAINS Hodgkin-Huxley Neuron Builder (HHNB), a web resource for building single cell neural models via the extraction of activity features from electrophysiological traces, the optimization of the model parameters via a genetic algorithm executed on high performance computing facilities and the simulation of the optimized model in an interactive framework. Thanks to its inherent characteristics, the HHNB facilitates the data-driven model building workflow and its reproducibility, hence fostering a collaborative approach to brain modeling.

FRONTIERS MEDIA SA2022

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Voltage-sensitive dye imaging of mouse neocortex during a whisker detection task

Matthieu Pierre Auffret, Alexandros Kyriakatos, Alessandro Motta, Carl Petersen, Vijay Sadashivaiah, Yifei Zhang

Sensorimotor processing occurs in a highly distributed manner in the mammalian neocortex. The spatiotemporal dynamics of electrical activity in the dorsal mouse neocortex can be imaged using voltage-sensitive dyes (VSDs) with near-millisecond temporal resolution and similar to 100-mu m spatial resolution. Here, we trained mice to lick a water reward spout after a 1-ms deflection of the C2 whisker, and we imaged cortical dynamics during task execution with VSD RH1691. Responses to whisker deflection were highly dynamic and spatially highly distributed, exhibiting high variability from trial to trial in amplitude and spatiotemporal dynamics. We differentiated trials based on licking and whisking behavior. Hit trials, in which the mouse licked after the whisker stimulus, were accompanied by overall greater depolarization compared to miss trials, with the strongest hit versus miss differences being found in frontal cortex. Prestimulus whisking decreased behavioral performance by increasing the fraction of miss trials, and these miss trials had attenuated cortical sensorimotor responses. Our data suggest that the spatiotemporal dynamics of depolarization in mouse sensorimotor cortex evoked by a single brief whisker deflection are subject to important behavioral modulation during the execution of a simple, learned, goal-directed sensorimotor transformation. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.

SPIE-Intl Soc Optical Eng2017

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Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing

Sylvain Crochet, Célia Roxane Gasselin, Benoît Hohl, Carl Petersen

Fast synaptic transmission relies upon the activation of ionotropic receptors by neurotransmitter release to evoke postsynaptic potentials. Glutamate and GABA play dominant roles in driving highly dynamic activity in synaptically connected neuronal circuits, but ionotropic receptors for other neurotransmitters are also expressed in the neocortex, including nicotinic receptors, which are non-selective cation channels gated by acetylcholine. To study the function of non-glutamatergic excitation in neocortex, we used two-photon microscopy to target whole-cell membrane potential recordings to different types of genetically defined neurons in layer 2/3 of primary somatosensory barrel cortex in awake head-restrained mice combined with pharmacological and optogenetic manipulations. Here, we report a prominent nicotinic input, which selectively depolarizes a subtype of GABAergic neuron expressing vasoactive intestinal peptide leading to disinhibition during active sensorimotor processing. Nicotinic disinhibition of somatosensory cortex during active sensing might contribute importantly to integration of top-down and motor-related signals necessary for tactile perception and learning.

CELL PRESS2021

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CS-486: Interaction design

This course focuses on goal-directed design and interaction design, two subjects treated in depth in the Cooper book (see reference below). To practice these two methods, we propose a design challenge, which is further divided into mini-projects evenly spaced throughout the semester.

COM-401: Cryptography and security

This course introduces the basics of cryptography. We review several types of cryptographic primitives, when it is safe to use them and how to select the appropriate security parameters. We detail how they work and sketch how they can be implemented.

MICRO-435: Quantum and nanocomputing

The course teaches non von-Neumann architectures. The first part of the course deals with quantum computing, sensing, and communications. The second focuses on field-coupled and conduction-based nanocomputing, in-memory and molecular computing, cellular automata, and spintronic computing.