Concept

Circumstantial evidence

Publications associées (142)

High Sensitivity Detection of a Solubility Limiting Surface Transformation of Drug Particles by DNP SENS

David Lyndon Emsley, Arthur César Pinon, Jasmine Viger-Gravel

We investigate the presence of a surface species for the active pharmaceutical ingredient (API) AZD9496 with dynamic nuclear polarization surface enhanced nuclear spectroscopy (DNP SENS). We show that using DNP we can elucidate the presence of an amorphous ...

ELSEVIER SCIENCE INC2021

The concept of the mobilized domain: how it can explain and predict the forces exerted by a cohesive granular avalanche on an obstacle.

Christophe Ancey, Johan Alexandre Philippe Gaume, Betty Sovilla, Michael Lukas Kyburz

The calculation of the impact pressure on obstacles in granular flows is a fundamental issue of practical relevance, e.g. for snow avalanches impacting obstacles. Previous research shows that the load on the obstacle builds up, due to the formation of forc ...

2021

FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade

Henning Paul-Julius Stahlberg, Amanda Jennifer Lewis, Marta Di Fabrizio, Julien Weber

Morphologically distinct TDP-43 aggregates occur in clinically different FTLD-TDP subtypes, yet the mechanism of their emergence and contribution to clinical heterogeneity are poorly understood. Several lines of evidence suggest that pathological TDP-43 fo ...

WILEY2021

Expectations with Endogenous Information Acquisition: An Experimental Investigation

Andreas Fuster

We use a survey experiment to generate direct evidence on how people acquire and process information. Participants can buy different information signals that could help them forecast future national home prices. We elicit their valuations and exogenously v ...

2020

Unravelling the role of phoretic and hydrodynamic interactions in active colloidal suspensions

Ignacio Pagonabarraga Mora

Active fluids comprise a variety of systems composed of elements immersed in a fluid environment which can convert some form of energy into directed motion; as such they are intrinsically out-of-equilibrium in the absence of any external force. A fundament ...

ROYAL SOC CHEMISTRY2020

Innovation, industry and firm age: are there new knowledge production functions?

Gabriele Pellegrino

In this paper we investigate how the knowledge production function is at work in different industrial sectors comparing mature and young companies in Italy. We estimate a two-step model using community innovation survey data. We provide evidence that young ...

SPRINGER HEIDELBERG2020

Crowding reveals fundamental differences in local vs. global processing in humans and machines

Michael Herzog, Aurélien Bornet, Adrien Christophe Doerig, Oh-Hyeon Choung

Feedforward Convolutional Neural Networks (ffCNNs) have become state-of-the-art models both in computer vision and neuroscience. However, human-like performance of ffCNNs does not necessarily imply human-like computations. Previous studies have suggested t ...

2020

Koopman Analysis of Isolated Fronts and Solitons

A Koopman decomposition of a complex system leads to a representation in which nonlinear dynamics appear to be linear. The existence of a linear framework with which to analyze nonlinear dynamical systems brings new strategies for prediction and control, w ...

2020

A new spin on fidgets

Mackenzie Mathis

We express decisions through movements, but not all movements matter to the outcome. For example, fidgeting is a common yet ‘nonessential’ behavior we exhibit. New evidence suggests that this non-task-related movement profoundly shapes neural activity in e ...

2019

Clothing-Mediated Exposures to Chemicals and Particles

Dusan Licina

A growing body of evidence identifies clothing as an important mediator of human exposure to chemicals and particles, which may have public health significance. This paper reviews and critically assesses the state of knowledge regarding how clothing, durin ...

2019

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