Concept

Theistic evolution

Publications associées (188)

Toward dynamic isotopomer analysis in the rat brain in vivo: automatic quantitation of 13C NMR spectra using LCModel

The LCModel method was adapted to analyze localized in vivo (13)C NMR spectra obtained from the rat brain in vivo at 9.4 T. Prior knowledge of chemical-shifts, J-coupling constants and J-evolution was included in the analysis. Up to 50 different isotopomer ...

Wiley-Blackwell2003

Directed Evolution of O6-Alkylguanine-DNA Alkyltransferase for Efficient Labeling of Fusion Proteins with Small Molecules In Vivo

Horst Vogel, Kai Johnsson, Horst Pick, Alexandre Juillerat, Thomas Gronemeyer, Antje Keppler

We report here the generation of mutants of the human O6-alkylguanine-DNA alkyltransferase (hAGT) for the efficient in vivo labeling of fusion proteins with synthetic reporter mols. Libraries of hAGT were displayed on phage, and mutants capable of efficien ...

2003

Biphasic constitutive laws for biological interface evolution

Dominique Pioletti, Lalaonirina Rakotomanana Ravelonarivo, Philippe Büchler

A model of tissue differentiation at the bone-implant interface is proposed. The basic hypothesis of the model is that the mechanical environment determines the tissue differentiation. The stimulus chosen is related to the bone-implant micromotions. Equati ...

2003

Acoustic Based Rendering by Interpolation of the Plenacoustic Function

Martin Vetterli, Thibaut Ajdler

We study the spatialization of the sound field in a room, in particular the evolution of room impulse responses as function of their spatial positions. The presented technique allows us to completely characterize the sound field in any arbitrary location i ...

2003

De l'acoustique des églises en Suisse

Victor Desarnaulds

The existence of the fundamental conflict in churches between the desirable acoustic conditions for music and for speech intelligibility prompted this dissertation. It tackles the subject not only under the acoustical perspective but also in the historical ...

EPFL2002

The Plenacoustic Function and its Sampling

Martin Vetterli, Thibaut Ajdler

In this paper, we study the spatialization of the sound field in rooms, in particular the evolution of the room impulse responses in function of their spatial positions. Thanks to this study, we are now able to predict the sound field in any position knowi ...

2002

Type-Safe Prototype-Based Component Evolution

Matthias Zenger

Component-based programming is currently carried out us- ing mainstream object-oriented languages. These languages have to be used in a highly disciplined way to guarantee flexible component composition and extensibility. This paper investigates abstractio ...

Springer Berlin Heidelberg2002

Type-Safe Prototype-Based Component Evolution

Matthias Zenger

Component-based programming is currently carried out using mainstream object-oriented languages. These languages have to be used in a highly disciplined way to guarantee flexible component composition and extensibility. This paper investigates abstractions ...

2002

Changing the substrate specificity of cytochrome c peroxidase using directed evolution

Kai Johnsson, Petra Tafelmeyer

Cytochrome c peroxidase (I) from Saccharomyces cerevisiae was subjected to directed mol. evolution to generate mutants with increased activity against ABTS [2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)]. Using a combination of DNA shuffling and s ...

2001

Evolutionary approaches to study cytochrome c peroxidase

Kai Johnsson, Petra Tafelmeyer

A review with 15 refs. Directed mol. evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies. To demonstrate the underlying p ...

2001

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