Concept

Don d'organes

Publications associées (36)

Chronic wound healing by fetal cell therapy may be explained by differential gene profiling observed in fetal versus old skin cells

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri

Engineering of fetal tissue has a high potential for the treatment of acute and chronic wounds of the skin in humans as these cells have high expansion capacity under simple culture conditions and one organ donation can produce Master Cell Banks which can ...

2009

Whole-cell bioprocessing of human fetal cells for tissue engineering of skin

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity (simple culture conditions), maintenance of differentiated phenotype for primary human cell culture and trans ...

2009

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

Jacques Fellay, Amalio Telenti

A variant 35 kb upstream of the HLA-C gene (-35C/T) was previously shown to associate with HLA-C mRNA expression level and steady-state plasma HIV RNA levels. We genotyped this variant in 1,698 patients of European ancestry with HIV. Individuals with known ...

2009

Electron localization by a donor in the vicinity of a basal stacking fault in GaN

Benoît Marie Joseph Deveaud, Jean-Daniel Ganière, Pierre Michel Corfdir, Jelena Ristic

We study the effects of the vicinity between a shallow donor nucleus and an I1-type basal stacking fault (BSF) in GaN. We propose a numerical calculation, in the “effective potential” formalism, of energies and envelope functions of electrons submitted to ...

2009

Isolation and in vitro chondrogenic potential of human fetal spine cells

Dominique Pioletti, Corinne Scaletta, Sandra Jaccoud, Aurélie Quintin

Cell therapy for nucleus pulposus regeneration is an attractive treatment for early disc degeneration as shown by studies using autologous nucleus pulposus cells or stem cells. Another potential source of cells is fetal cells. We investigated the feasibili ...

2009

Consistency of fetal cell banks for research and clinical use

Dominique Pioletti, Corinne Scaletta, Aurélie Quintin

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity and maintenance of differentiated phenotype for primary human cell culture. In our experience, we have seen t ...

2007

Organ Transplantation Management

Rachele Fuzzati

Organ transplantation is a widespread and effective technique to treat important diseases and can often make the difference between life and death of some patients. Given a donor, finding the best recipient for one of his organs means finding, in the short ...

2005

Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions

Patrick Aebischer, Bernard Schneider

Allogeneic cells are the most attractive source for cell transplantation, as the use of xenogeneic cells is hampered by safety concerns and the use of autologous cells involves practical difficulties. The immune rejection of allogeneic cells can be overcom ...

2004

De l'acoustique des églises en Suisse

Victor Desarnaulds

The existence of the fundamental conflict in churches between the desirable acoustic conditions for music and for speech intelligibility prompted this dissertation. It tackles the subject not only under the acoustical perspective but also in the historical ...

EPFL2002

Conditional autoimmunity mediated by human natural anti-Fc(epsilon)RIalpha autoantibodies?

Florian Maria Wurm, Martin Vogel

Natural antibodies provide an early defense mechanism against pathogens, show a frequent self-reactivity, and are present throughout life. Two questions concern the physiological control of self-reactivity and the pathogenetic link to autoimmune disease. H ...

2001

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