Publications associées à Dépression synaptique à long terme

Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Cognitive difficulties are the most common neurological complications in neurofibromatosis type 1 (NF1) patients. Recent animal models proposed increased GABA-mediated inhibition as one underlying mechanism directly affecting the induction of long-term pot ...

2015

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

Jeffrey Alan Hubbell, Mikaël Martino, Alice Anna Tomei

With a view toward reduction of graft loss, we explored pancreatic islet transplantation within fibrin matrices rendered pro-angiogenic by incorporation of minimal doses of vascular endothelial growth factor-A165 and platelet-derived growth factor-BB prese ...

Wiley-Blackwell2015

An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

Henry Markram, Felix Schürmann, Ralf Schneggenburger, Daniel Keller, Olexiy Kochubey, Yunyun Han, Zsolt Norbert Babai

The spatial arrangement of Ca2+ channels and vesicles remains unknown for most CNS synapses, despite of the crucial importance of this geometrical parameter for the Ca2+ control of transmitter release. At a large model synapse, the calyx of Held, transmitt ...

Public Library Science2015

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

Carl Petersen, Aurélie Pala

Intracellular recordings of membrane potential in vitro have defined fundamental properties of synaptic communication. Much less is known about the properties of synaptic connectivity and synaptic transmission in vivo. Here, we combined single-cell opto-ge ...

Cell Press2015

Differential effects of BDNF val(66)met in repetitive associative learning paradigms

Friedhelm Christoph Hummel, Winifried Backhaus

In healthy young subjects, the brain derived neurotropic factor (BDNF) val(66)met polymorphism negatively affects behavioural outcome in short-term motor cortex or hippocampus-based learning paradigms. In repetitive training paradigms over several days thi ...

Elsevier2015

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Blood oxygenation level-dependent (BOLD) functional MRI is a widely employed methodology in experimental and clinical neuroscience, although its nature is not fully understood. To gain insights into BOLD mechanisms and take advantage of the new functional ...

Wiley-Blackwell2015

Effectiveness of variable speed limits considering commuters' long-term response

Wei Liu

This paper examines the effectiveness of variable speed limits (VSLs) on improving traffic flow efficiency and reducing vehicular emissions in a stylized setting of morning commute where a fixed number of individuals commute from home to work through the f ...

Pergamon-Elsevier Science Ltd2015

Synaptic consolidation: from synapses to behavioral modeling

Wulfram Gerstner, Friedemann Zenke, Lorric Ziegler, David Barak Kastner

Synaptic plasticity, a key process for memory formation, manifests itself across different time scales ranging from a few seconds for plasticity induction up to hours or even years for consolidation and memory retention. We developed a three-layered model ...

Society for Neuroscience2015

A microfluidic device for longitudinal studies of C.elegans neurodegenerative disease models

Johan Auwerx, Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Laurent Mouchiroud, Govindan Narayanan Krishnamani

We describe a microfluidic device for automated culture and long-term high resolution imaging of Caenorhabditis elegans nematodes, which we specifically employed as model organisms for the analysis of neurodegenerative disease progression. In this platform ...

2015

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Dépression synaptique à long terme

Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

Differential effects of BDNF val(66)met in repetitive associative learning paradigms

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

Effectiveness of variable speed limits considering commuters' long-term response

Synaptic consolidation: from synapses to behavioral modeling

A microfluidic device for longitudinal studies of C.elegans neurodegenerative disease models

Biomaterials. Electronic dura mater for long-term multimodal neural interfaces

Graph Chatbot

Chattez avec Graph Search

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

Synaptic consolidation: from synapses to behavioral modeling

Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

Biomaterials. Electronic dura mater for long-term multimodal neural interfaces

Differential effects of BDNF val(66)met in repetitive associative learning paradigms

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

Effectiveness of variable speed limits considering commuters' long-term response

A microfluidic device for longitudinal studies of C.elegans neurodegenerative disease models