Concept

Groupe sanguin

Publications associées (122)

Spatial analysis of erythrocyte membrane fluctuations by digital holographic microscopy

Pierre Magistretti, Christian Depeursinge, Benjamin Rappaz, Pierre Marquet, Daniel Boss, Annick Hoffmann

Red blood cell (RBC) membrane fluctuations provide important insights into cell states. We present a spatial analysis of red blood cell membrane fluctuations by using digital holographic Microscopy (DHM). This interferometric and dye-free technique, posses ...

Elsevier2009

IFN alpha activates dormant haematopoietic stem cells in vivo

Sandra Eloise Kjeldsen

Maintenance of the blood system is dependent on dormant haematopoietic stem cells (HSCs) with long-term self-renewal capacity. After injury these cells are induced to proliferate to quickly reestablish homeostasis(1). The signalling molecules promoting the ...

2009

Extraction of haemoglobin from human blood by affinity precipitation using a haptoglobin-based stimuli-responsive affinity macroligand

Gisela Stocker Majd

Affinity precipitation was compared to affinity chromatography and batch adsorption as the final purification step in a protocol for the isolation of haemoglobin from human blood. Haptoglobin was the affinity ligand. The first steps on the process were rea ...

2008

Comparative study of human erythrocytes by digital holographic microscopy, confocal microscopy, and impedance volume analyzer

Pierre Magistretti, Christian Depeursinge, Benjamin Rappaz, Pierre Marquet

Red blood cell (RBC) parameters such as morphology, volume, refractive index, and hemoglobin content are of great importance for diagnostic purposes. Existing approaches require complicated calibration procedures and robust cell perturbation. As a result, ...

2008

Microparticles in stored red blood cells: an approach using flow cytometry and proteomic tools

Niels Erik Lion, David Crettaz, Olivier Rubin

Background and Objectives Microparticles (MPs) are small phospholipid vesicles of less than 1 mu m, shed in blood flow by various cell types. These MPs are involved in several biological processes and diseases. MPs have also been detected in blood products ...

Wiley-Blackwell2008

In vivo MRI assessment of a novel GdIII-based contrast agent designed for high magnetic field applications

André Merbach, Lothar Helm, Eva Jakab Toth, Joao Bruno Livramento Fig.

Gd3L is a trinuclear Gd3R complex of intermediate size, designed for contrast agent applications in high field magnetic resonance imaging (H12L is based on a trimethylbenzene core bearing three methylene-diethylenetriamine-N,N,N00,N00-tetraacetate moieties ...

2008

Using forward calculations of the magnetic field perturbation due to a realistic vascular model to explore the BOLD effect

José Pedro Rebelo Ferreira Marques

This paper assesses the reliability of the infinite cylinder model used previously in the literature to simulate blood oxygenation level dependent (BOLD) signal changes. A three-dimensional finite element method was applied to a realistic model of the cort ...

Wiley-Blackwell2008

Rapid Immunoassay Using Steady-State Dispersion Effects in Nanochannels

Philippe Renaud, Nicolas Durand, Ana Valero

We present a novel method for on-chip competitive dispersion immunoassay (DISIA) which aims at measuring the specificity between fluorescently-labeled antibodies (Ab*) and label-free antigens (Ag). We have fabricated a nanofluidic device that allows fast d ...

2008

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer

Michele De Palma, Ferdinando Pucci

Tumor-infiltrating myeloid cells, including tumor-associated macrophages (TAMs), have been implicated in tumor progression. We recently described a lineage of mouse monocytes characterized by expression of the Tie2 angiopoietin receptor and required for th ...

American Society of Hematology2007

Multiscale modelling of metabolism and transport phenomena in living tissues

Carlo D'Angelo

The range of applications of mathematical modelling in biosciences has recently expanded to encompass problems posed by biomedicine and sport sciences. Topics of interest are for instance the prediction of the response of an athlete to exercise, the pharma ...

EPFL2007

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