Publications associées à Glutamine

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

Cristina Ramona Cudalbu, Bernard Lanz, Veronika Rackayová

In vivo Magnetic Resonance Spectroscopy is a useful tool to characterize brain biochemistry as well as its alteration in a large number of major central nervous system diseases. The present review will focus on the study of the glutamate-glutamine cycle, a ...

Elsevier2017

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employ ...

Wiley-Blackwell2017

LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer

Johan Auwerx, Kristina Schoonjans, Hadrien Charles Edouard Demagny, Arnaud Comment, Dongryeol Ryu, Xu Wang, Norman Lionel Moullan, Emine Can, Matthias Alexander Sokrates Stein, Maaike Hélène Oosterveer, Pan Xu

Various tumors develop addiction to glutamine to support uncontrolled cell proliferation. Here we identify the nuclear receptor liver receptor homolog 1 (LRH-1) as a key regulator in the process of hepatic tumorigenesis through the coordination of a noncan ...

Cold Spring Harbor Laboratory2016

A New Caged-Glutamine Derivative as a Tool To Control the Assembly of Glutamine-Containing Amyloidogenic Peptides

Hilal Lashuel, Loay Awad, Ritwik Burai, Nino Jejelava

We present the design, synthesis, and characterization of a novel photocaged glutamine derivative (modified on the side chain of glutamine), and describe its use in enhancing peptide stability and solubility. Our results demonstrate that this approach can ...

Wiley-Blackwell2016

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Many tissues exhibit metabolic compartmentation. In the brain, while there is no doubt on the importance of functional compartmentation between neurons and glial cells, there is still debate on the specific regulation of pathways of energy metabolism at di ...

Nature Publishing Group2016

Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

Rolf Gruetter, João Miguel das Neves Duarte, Freya-Merret Girault

The brain uses lactate produced by glycolysis as an energy source. How lactate originated from the blood stream is used to fuel brain metabolism is not clear. The current study measures brain metabolic fluxes and estimates the amount of pyruvate that becom ...

Wiley-Blackwell2015

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

Rolf Gruetter, Cristina Ramona Cudalbu, Mélanie Craveiro

Glutamine has multiple roles in brain metabolism and its concentration can be altered in various pathological conditions. An accurate knowledge of its concentration is therefore highly desirable to monitor and study several brain disorders in vivo. However ...

Wiley-Blackwell2014

Glutamatergic and GABAergic energy metabolism measured in the rat brain by 13C NMR spectroscopy at 14.1 T

Rolf Gruetter, João Miguel das Neves Duarte

Energy metabolism supports both inhibitory and excitatory neurotransmission processes. This study investigated the specific contribution of astrocytic metabolism to γ-aminobutyric acid (GABA) synthesis and inhibitory GABAergic neurotransmission that remain ...

Wiley-Blackwell2013

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Glutamine

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Experimental and theoretical studies on electropolymerization of polar amino acids on platinum electrode

LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer

Deciphering the Role of LRH-1 in Liver Intermediary Metabolism and Cancer

A New Caged-Glutamine Derivative as a Tool To Control the Assembly of Glutamine-Containing Amyloidogenic Peptides

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

Glutamatergic and GABAergic energy metabolism measured in the rat brain by 13C NMR spectroscopy at 14.1 T

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Chattez avec Graph Search

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

Deciphering the Role of LRH-1 in Liver Intermediary Metabolism and Cancer

Experimental and theoretical studies on electropolymerization of polar amino acids on platinum electrode

A New Caged-Glutamine Derivative as a Tool To Control the Assembly of Glutamine-Containing Amyloidogenic Peptides

MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic models

Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

Glutamatergic and GABAergic energy metabolism measured in the rat brain by 13C NMR spectroscopy at 14.1 T

LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer