Concept

Théorie métabolique de l'écologie

Publications associées (44)

Towards a metabolic theory of catchments: scaling of water and carbon fluxes with size

Allometric scaling relations are widely used to link biological processes in nature. They are typically expressed as power laws, postulating that the metabolic rate of an organism scales as its mass to the power of an allometric exponent, which ranges betw ...

2024

Towards a metabolic theory of catchments: scaling of water and carbon fluxes with size

Sara Bonetti, Francesca Bassani

Catchments are heterogeneous ecosystems involving several abiotic and biotic processes, where the mutual interactions among water, vegetation, and biogeochemical fluxes take place at different scales. Many biological processes in nature are characterized b ...

2023

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand

IntroductionDesulfitobacterium hafniense was isolated for its ability to use organohalogens as terminal electron acceptors via organohalide respiration (OHR). In contrast to obligate OHR bacteria, Desulfitobacterium spp. show a highly versatile energy meta ...

FRONTIERS MEDIA SA2023

Seeing the forest for the trees through metabolic scaling

Andrea Rinaldo, Amos Maritan

We demonstrate that when power scaling occurs for an individual tree and in a forest, there is great resulting simplicity notwithstanding the underlying complexity characterizing the system over many size scales. Our scaling framework unifies seemingly dis ...

2022

Constraint-based metabolic control analysis for rational strain engineering

Vassily Hatzimanikatis, Ljubisa Miskovic, Meriç Ataman, Tuure Eelis Hameri, Sofia Tsouka

The advancements in genome editing techniques over the past years have rekindled interest in rational metabolic engineering strategies. While Metabolic Control Analysis (MCA) is a well-established method for quantifying the effects of metabolic engineering ...

2021

Theory-based scaling laws of near and far scrape-off layer widths in single-null L-mode discharges

Paolo Ricci, Holger Reimerdes, Jan Horacek, Cedric Kar-Wai Tsui, Maurizio Giacomin, Adriano Stagni

Theory-based scaling laws of the near and far scrape-off layer (SOL) widths are analytically derived for L-mode diverted tokamak discharges by using a two-fluid model. The near SOL pressure and density decay lengths are obtained by leveraging a balance amo ...

2021

Mapping and Analysis of the Complexity of Lipid Metabolism for Applications in Health and Sustainability

Vassily Hatzimanikatis, Sofia Tsouka

Metabolism is a network of biotransformations that sustain life in cells. Over the past decades, metabolism has been studied in multiple contexts, ranging from medicine to industrial manufacturing. In particular, lipid metabolism has been linked to various ...

EPFL2020

Modeling biochemical reaction networks in complex intracellular environments

Daniel Robert Weilandt

Whether one aims to design treatments for diseases such as cancer or diabetes, engineer cells to produce valuable biochemicals sustainably, or to grasp the behavior of living organisms, it is essential to understand how cells react to genetic, environmenta ...

EPFL2020

Allometric Scaling of physiologically-relevant organoids

Andrea Rinaldo

The functional and structural resemblance of organoids to mammalian organs suggests that they might follow the same allometric scaling rules. However, despite their remarkable likeness to downscaled organs, non-luminal organoids are often reported to posse ...

2019

Generalized size scaling of metabolic rates based on single-cell measurements with freshwater phytoplankton

Anders Meibom, Andrea Rinaldo, Stéphane Laurent Escrig, Andrea Giometto, Silvia Zaoli, Emilio Marañón, Amos Maritan

Kleiber's law describes the scaling of metabolic rate with body size across several orders of magnitude in size and across taxa and is widely regarded as a fundamental law in biology. The physiological origins of Kleiber's law are still debated and general ...

PNAS2019

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