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The study of genomic inversions (or reversals) has been a mainstay of computational genomics for nearly 20 years. After the initial breakthrough of Hannenhalli and Pevzner, who gave the first polynomial-time algorithm for sorting signed permutations by inv ...
This paper's focus is the following family of problems, denoted k-ECSS, where k denotes a positive integer: given a graph (V, E) and costs for each edge, find a minimum-cost subset F of E such that (V, F) is k-edge-connected. For k=1 it is the spanning tre ...
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We give the first constant factor approximation algorithm for the asymmetric Virtual Private Network (VPN) problem with arbitrary concave costs. We even show the stronger result, that there is always a tree solution of cost at most 2 OPT and that a tree so ...
A long-standing open question in information theory is to characterize the unicast capacity of a wireless relay network. The difficulty arises due to the complex signal interactions induced in the network, since the wireless channel inherently broadcasts t ...
We study complexity and approximation of MIN WEIGHTED NODE COLORING in planar, bipartite and split graphs. We show that this problem is NP-hard in planar graphs, even if they are triangle-free and their maximum degree is bounded above by 4. Then, we prove ...
The generalized hypertree width GHW(H) of a hypergraph H is a measure of its cyclicity. Classes of conjunctive queries or constraint satisfaction problems whose associated hypergraphs have bounded GHW are known to be solvable in polynomial time. However, i ...
We give a rigorous account on the complexity landscape of an important real-time scheduling problem that occurs in the design of software-based aircraft control. The goal is to distribute tasks τi=(ci,pi) on a minimum number of identical machines a ...
A binary tanglegram is a pair (S, T) of binary trees whose leaf sets are in one-to-one correspondence; matching leaves are connected by inter-tree edges. For applications, for example in phylogenetics, it is essential that both trees are drawn without edge ...
This article concerns the following question arising in computational evolutionary biology. For a given subclass of phylogenetic networks, what is the maximum value of 0
The study of genomic inversions (or reversals) has been a mainstay of computational genomics for nearly 20 years. After the initial breakthrough of Hannenhalli and Pevzner, who gave the first polynomial-time algorithm for sorting signed permutations by inv ...