Concept

Carcinome basocellulaire

Publications associées (111)

Functionalized bismuth ferrite harmonic nanoparticles for cancer cells labelling and imaging

Sandrine Gerber, Solène Marcelle Françoise Marie Passemard, Luigi Bonacina, Giona Sonego

Bismuth ferrite (BFO) harmonic nanoparticles (NPs) display high nonlinear optical efficiency and excellent biocompatibility profile which make them attractive for the development of diagnostic applications as contrast agents. In this study, we present a ge ...

Springer Verlag2015

Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors

Cathrin Brisken

We are now witnessing a resurgence of theories of development and carcinogenesis in which the environment is again being accepted as a major player in phenotype determination. Perturbations in the fetal environment predispose an individual to disease that ...

Springer Verlag2013

Numerically bridging lamellipodial and filopodial activity during cell spreading reveals a potentially novel trigger of focal adhesion maturation

Benoît Vianay

We present a novel approach to modeling cell spreading, and use it to reveal a potentially central mechanism regulating focal adhesion maturation in various cell phenotypes. Actin bundles that span neighboring focal complexes at the lamellipodium-lamellum ...

2012

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

Yann Barrandon, Friedrich Beermann, Stéphanie Claudinot, Lukas Sommer

Giant congenital naevi are pigmented childhood lesions that frequently lead to melanoma, the most aggressive skin cancer. The mechanisms underlying this malignancy are largely unknown, and there are no effective therapies. Here we describe a mouse model fo ...

Nature Publishing Group2012

Innovative TiO2/Cu Nanosurfaces Inactivating Bacteria in the Minute Range under Low-Intensity Actinic Light

César Pulgarin, Juan Kiwi, Sami Rtimi, Rosendo Sanjines, Oualid Baghriche

The bacterial inactivation of E. coli by cotton TiO2/Cu DC-magnetron sputtered thin films was investigated in the dark and under low-intensity actinic light. The TiO2/Cu sputtered layers revealed to be sensitive to actinic light showing the spectral charac ...

Amer Chemical Soc2012

Protein-Binding Microarray Analysis of Tumor Suppressor AP2 alpha Target Gene Specificity

Horst Vogel, Luigino Grasso, Jan Kerschgens, Tanja Egener-Kuhn, Nicolas Mermod, Hans-Anton Lehr

Cheap and massively parallel methods to assess the DNA-binding specificity of transcription factors are actively sought, given their prominent regulatory role in cellular processes and diseases. Here we evaluated the use of protein-binding microarrays (PBM ...

Public Library of Science2011

Effects of Photodynamic Therapy in Combination with Anti-Angiogenic Drugs on the Chicken Chorioallantoic Membrane Model

Photodynamic therapy (PDT) is clinically-approved in the treatment of angiogenic disorders, particularly eye diseases such as age-related macular degeneration (AMD) and skin cancers, such as basal cell carcinoma. PDT causes vascular occlusion resulting in ...

2011

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

Paloma Ordonez Moran

BACKGROUND: Cyclooxygenase-2 (COX-2) overexpression in colorectal cancer increases levels of its pro-tumorigenic product prostaglandin E2 (PGE(2)). The recently identified colorectal tumour suppressor 15-prostaglandin dehydrogenase (15-PGDH) catalyses pros ...

BMJ Publishing Group2011

DCE-MRI using small-molecular and albumin-binding contrast agents in experimental carcinomas with different stromal content

Alessandro Daducci

OBJECTIVES: To compare DCE-MRI experiments performed using a standard small-molecular (Gd-DTPA) and an albumin-binding (MS-325) contrast agent in two carcinoma models with different stromal content. MATERIALS AND METHODS: DU-145 or BXPC-3 cancer cells were ...

Elsevier2011

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

Cathrin Brisken, Maryse Fiche

The breast epithelium has two major compartments, luminal and basal cells, that are established and maintained by poorly understood mechanisms. The p53 homolog, p63, is required for the formation of mammary buds, but its function in the breast after birth ...

Nature Publishing Group2010

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