Publications de Aleksandra Radenovic

Resolution in super-resolution microscopy – facts, artifacts, technological advancements and biological applications

Super-resolution microscopy (SRM) has undeniable potential for scientific discovery, yet still presents many challenges that hinder its widespread adoption, including technical trade-offs between resolution, speed and photodamage, as well as limitations in ...

The Company of Biologists2025

Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging

Hilal Lashuel, Aleksandra Radenovic, Lely Feletti, Khalid Ashraf Mohie Ibrahim

The process of protein aggregation, central to neurodegenerative diseases like Huntington’s, is challenging to study due to its unpredictable nature and relatively rapid kinetics. Understanding its biomechanics is crucial for unraveling its role in disease ...

Springer Science and Business Media LLC2025

Sum-Frequency Scattering Spectroscopy Reveals the Charging Mechanism and Surface Structure of hBN Nanoflakes in Solution

Sylvie Roke, Aleksandra Radenovic, Nathan Cyprien Arsène Ronceray, Li Zhang, Benjamin Rehl

A molecular understanding of the interactions between two-dimensional (2D) layered materials and liquids is crucial for nanofluidics, catalysis, and solution-based 2D material processing. Among 2D materials, hexagonal boron nitride (hBN) has a number of ou ...

American Chemical Society (ACS)2025

Controlled Sensing of User-Defined Aptamer-Based Targets Using Scanning Ionic Conductance Spectroscopy

Aleksandra Radenovic, Georg Fantner, Lely Feletti, Marcos Penedo Garcia, Wayne Yang Wen Wei, Barney Frederick Drake, Helena Miljkovic, Zahra Ayar Dulabi

Solid-state nanopores offer the possibility of detecting disease biomarkers in early diagnostic applications. Standard approaches harness fingerprinting, where protein targets are bound to DNA carriers and detected in free translocation with a solid-state ...

2025

Assessment of neurobehavioural traits under gnotobiotic conditions: an approach for multiple analyses in the same mouse

Aleksandra Radenovic, Raphaël Doenlen, Arielle Louise Planchette

The gut-microbiota-brain axis influences neuroinflammation, neural development and behaviour such as sociability, memory and anxiety. To study these traits in vivo, especially during development or disease, it is crucial to analyse them over time and with ...

2025

Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera

Edoardo Charbon, Claudio Bruschini, Aleksandra Radenovic, Matteo Dal Peraro, Nathan Cyprien Arsène Ronceray

Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool to discriminate fluorescent molecules or probe their nanoscale environment. Traditionally, FLIM uses time-correlated single-photon counting (TCSPC), which is precise but intrinsically low-t ...

2025

Fast Tracking with SPADs from Binary 1-Bit Per Pixel Output: Single-Photon Single-Particle Tracking

Aleksandra Radenovic, Nathan Cyprien Arsène Ronceray

Oxford University Press (OUP)2025

Open-source microscope add-on for structured illumination microscopy

Theo Lasser, Matthias Lütolf, Aleksandra Radenovic, Andrew Charles Oates, Georg Fantner, John McKinney, Nathan Cyprien Arsène Ronceray, Olivier François Venzin, Antonius Chrisnandy, Prabhu Prasad Swain

Super-resolution techniques expand the abilities of researchers who have the knowledge and resources to either build or purchase a system. This excludes the part of the research community without these capabilities. Here we introduce the openSIM add-on to ...

Nature Portfolio2024

Nanofluidic logic with mechano-ionic memristive switches

Aleksandra Radenovic, Andras Kis, Andrey Chernev, Vasily Artemov, Edoardo Lopriore, Nathan Cyprien Arsène Ronceray, Yunfei Teng, Théo Denis Tobias Emmerich

Neuromorphic systems are typically based on nanoscale electronic devices, but nature relies on ions for energy-efficient information processing. Nanofluidic memristive devices could thus potentially be used to construct electrolytic computers that mimic th ...

Nature Portfolio2024

CVD graphene contacts for lateral heterostructure MoS2 field effect transistors

Aleksandra Radenovic, Andras Kis, Zhenyu Wang

Intensive research has been carried out on two-dimensional materials, in particular molybdenum disulfide, towards high-performance field effect transistors for integrated circuits 1 . Fabricating transistors with ohmic contacts is a challenging task due to ...

Nature Portfolio2024