Publications de Pamela Solange Valdés Undurraga

Production and Purification of Adeno-Associated Viral Vectors (AAVs) Using Orbitally Shaken HEK293 Cells

Bernard Schneider, Pamela Solange Valdés Undurraga

Humana Press2024

Gene therapy against amyotrophic lateral sclerosis: a bicistronic AAV vector for RNAi against mutated SOD1

Philippe Colin, Bernard Schneider, Pamela Solange Valdés Undurraga, Aline Aebi, Jean Philippe Gaudry

MARY ANN LIEBERT, INC2022

Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis

Osteoarthritis (OA) is the most common age-related joint disorder with no effective therapy. According to the World Health Organization, OA affects over 500 million people and is characterized by degradation of cartilage and other joint tissues, severe pai ...

WILEY2022

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Johan Auwerx, Pénélope Andreux, Davide D'Amico, Pamela Solange Valdés Undurraga, Anurag Singh

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its ...

2021

Analysis of deposited layers with deuterium and impurity elements on samples from the divertor of JET with ITER-like wall

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia

Inconel-600 blocks and stainless steel covers for quartz microbalance crystals from remote corners in the JET-ILW divertor were studied with time-of-flight elastic recoil detection analysis and nuclear reaction analysis to obtain information about the area ...

2019

Tritium distributions on W-coated divertor tiles used in the third JET ITER-like wall campaign

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Bruno Emanuel Ferreira De Sousa Correia, Patrick Blanchard

Tritium (T) distributions on tungsten (W)-coated plasma-facing tiles used in the third ITER-like wall campaign (2015-2016) of the Joint European Torus (JET) were examined by means of an imaging plate technique and beta-ray induced x-ray spectrometry, and t ...

Elsevier2019

Population modelling of the He II energy levels in tokamak plasmas: I. Collisional excitation model

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia

Helium is widely used as a fuel or minority gas in laboratory fusion experiments, and will be present as ash in DT thermonuclear plasmas. It is therefore essential to have a good understanding of its atomic physics. To this end He II population modelling h ...

IOP Publishing2019

Validation of the ICRF antenna coupling code RAPLICASOL against TOPICA and experiments

Olivier Sauter, Basil Duval, Stefano Coda, Timothy Goodman, Yves Martin, Jean-Marc Moret, Duccio Testa, Patrick Blanchard, Bruno Marchand, Holger Reimerdes

In this paper we validate the finite element code RAPLICASOL, which models radiofrequency wave propagation in edge plasmas near ICRF antennas, against calculations with the TOPICA code. We compare the output of both codes for the ASDEX Upgrade 2-strap ante ...

IOP Publishing Ltd2019

Role of the pedestal position on the pedestal performance in AUG, JET-ILW and TCV and implications for ITER

Stefano Coda, Patrick Blanchard, Benoît Labit, Antoine Pierre Emmanuel Alexis Merle, Umar Sheikh, Pamela Solange Valdés Undurraga, Lenke Horváth

The role of the pedestal position on the pedestal performance has been investigated in AUG, JET-ILW and TCV. When the pedestal is peeling-ballooning (PB) limited, the three machines show a similar behaviour. The outward shift of the pedestal density relati ...

IOP Publishing Ltd2019

G2019S LRRK2 enhances the neuronal transmission of tau in the mouse brain

Bernard Schneider, Pamela Solange Valdés Undurraga, Guillaume Daniel

2018