Publications de Jose Vicente Sanchez Mut

The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning

Johannes Gräff, Giulia Santoni, Allison Marie Burns, Jose Vicente Sanchez Mut

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...

2022

Comprehensive analysis of PM20D1 QTL in Alzheimer's disease

Johannes Gräff, Liliane Glauser, Jose Vicente Sanchez Mut

Background Alzheimer's disease (AD) is a complex disorder caused by a combination of genetic and non-genetic risk factors. In addition, an increasing evidence suggests that epigenetic mechanisms also accompany AD. Genetic and epigenetic factors are not ind ...

2020

Membrane activity detection in cultured cells using phase-sensitive plasmonics

Johannes Gräff, Liliane Glauser, Xiaokang Li, Jose Vicente Sanchez Mut, Yasaman Jahani, Ershad Mohammadi, Foziyeh Sohrabi

Despite the existence of various neural recording and mapping techniques, there is an open territory for the emergence of novel techniques. The current neural imaging and recording techniques suffer from invasiveness, a time-consuming labeling process, poo ...

2020

Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients

Johannes Gräff, Jose Vicente Sanchez Mut, Aurélie Delacrétaz, Céline Dubath

Background: Metabolic side effects induced by psychotropic drugs represent a major health issue in psychiatry. CREB-regulated transcription coactivator 1 (CRTC1) gene plays a major role in the regulation of energy homeostasis and epigenetic mechanisms may ...

2019

Analysis of deposited layers with deuterium and impurity elements on samples from the divertor of JET with ITER-like wall

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia

Inconel-600 blocks and stainless steel covers for quartz microbalance crystals from remote corners in the JET-ILW divertor were studied with time-of-flight elastic recoil detection analysis and nuclear reaction analysis to obtain information about the area ...

2019

Tritium distributions on W-coated divertor tiles used in the third JET ITER-like wall campaign

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Bruno Emanuel Ferreira De Sousa Correia, Patrick Blanchard

Tritium (T) distributions on tungsten (W)-coated plasma-facing tiles used in the third ITER-like wall campaign (2015-2016) of the Joint European Torus (JET) were examined by means of an imaging plate technique and beta-ray induced x-ray spectrometry, and t ...

Elsevier2019

Population modelling of the He II energy levels in tokamak plasmas: I. Collisional excitation model

Olivier Sauter, Ambrogio Fasoli, Basil Duval, Stefano Coda, Yves Martin, Jonathan Graves, Duccio Testa, Cristian Sommariva, Patrick Blanchard, Bruno Emanuel Ferreira De Sousa Correia

Helium is widely used as a fuel or minority gas in laboratory fusion experiments, and will be present as ash in DT thermonuclear plasmas. It is therefore essential to have a good understanding of its atomic physics. To this end He II population modelling h ...

IOP Publishing2019

A locked mode indicator for disruption prediction on JET and ASDEX upgrade

Olivier Sauter, Basil Duval, Ambrogio Fasoli, Stefano Coda, Timothy Goodman, Yves Martin, Jonathan Graves, Jean-Marc Moret, Patrick Blanchard, Holger Reimerdes

The aim of this paper is to present a signal processing algorithm that, applied to the raw Locked Mode signal, allows us to obtain a disruption indicator in principle exploitable on different tokamaks. A common definition of such an indicator for different ...

2019

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

Jose Vicente Sanchez Mut

Background: MeCP2-a chromatin-binding protein associated with Rett syndrome-has two main isoforms, MeCP2-E1 and MeCP2-E2, differing in a few N-terminal amino acid residues. Previous studies have shown brain region-specific expression of these isoforms whic ...

2019

Validation of the ICRF antenna coupling code RAPLICASOL against TOPICA and experiments

Olivier Sauter, Basil Duval, Stefano Coda, Timothy Goodman, Yves Martin, Jean-Marc Moret, Duccio Testa, Patrick Blanchard, Bruno Marchand, Holger Reimerdes

In this paper we validate the finite element code RAPLICASOL, which models radiofrequency wave propagation in edge plasmas near ICRF antennas, against calculations with the TOPICA code. We compare the output of both codes for the ASDEX Upgrade 2-strap ante ...

IOP Publishing Ltd2019