Fully Electronic CMOS DNA Detection Array Based on Capacitance Measurement with On-Chip Analog-to-Digital Conversion

An 8 times 16 array of sensing micro-sites employs a fully-electrical label-free technique for DNA recognition using capacitance measurement and is fabricated in 0.5mum CMOS with added noble metal. Repeatability and parallel detection capability have been demonstrated. The DNA-chip is suitable for low-cost, fully-integrated point-of-care applications