A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)

A rapid synthesis of aryl triflate and aryl nonaflate was developed using 4-nitrophenyl triflate and 4-nitrophenyl nonaflate as perfluoroalkanesulfonyl transfer reagents in combination with polymer supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PTBD). Simple filtration of the reaction mixt. gave the desired products in high chem. yields and purity. The unique role of PTBD as a base and side product scavenger was demonstrated. [on SciFinder (R)]