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Muscle synergies are thought to be the building blocks used by the central nervous system to control the underdetermined problem of muscles activation. Decoding these synergies from EEG could provide useful tools for BCI-controlled orthotic devices. In this paper, we assess the possibility of decoding muscle synergies from EEG slow cortical potentials in two healthy subjects and two stroke patients performing a center-out reaching task. We were able to successfully decode the extracted muscle synergies in both healthy subject and one patient.