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Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

Publications associées (61)

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In this paper, we define and assess a reference-based metric to evaluate the accuracy of pronoun translation (APT). The metric automatically aligns a candidate and a reference translation using GIZA++ augmented with specific heuristics, and then counts the ...

Idiap2016

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Noise in genetic networks has been the subject of extensive experimental and computational studies. However, very few of these studies have considered noise properties using mechanistic models that account for the discrete movement of ribosomes and RNA pol ...

Amer Inst Physics2015

This article aims to investigate the TED infrastructure for translating Science and Technology (S&T) projects (Callon, 1981, 1986; Law, 2006). The analysis uses the concepts of recognition (Honneth, 2012) and the public sphere as interpretative lenses for ...

2015

This paper seeks to investigate the TED infrastructure as a dispositif (Agamben, 2006; Bussolini, 2010)for translating Science and Technology (S&T) projects. We aim to adopt the concept of cultural capital as an interpretative lens for analyzing the dynami ...

2015

Mind the Gap? Translating science and technology projects with TED

Gianluigi Viscusi, Heidi Christina Gautschi

The term ‘translational research’ appeared in Pubmed for the first time around 1993 (van der Laan & Boenink, 2012). Translational research aims to identify and challenge the “translational gaps’’ (T gaps) hindering the transformation of discoveries in the ...

2015

Protein synthesis - computational modeling and experimental integration

Vassily Hatzimanikatis, Julien Racle

Proteins are among the central elements in every living cell as these ultimately determine how the cell functions. The protein abundances can be regulated at many levels, such as transcription, translation and degradation. As the complexity increases when ...

2014

Mathematical models and computational methods for the analysis of genome-scale protein synthesis

Julien Racle

Proteins are a ubiquitous and indispensable element for every living organism, from simple bacteria to mammals. Already in the simplest organisms, there exist some thousands of different protein species that take up a great variety of structures, and thus ...

EPFL2014

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Nonlinear microscopes have seen an increase in popularity in the life sciences due to their molecular and structural specificity, high resolution, large penetration depth, and volumetric imaging capability. Nonetheless, the inherently weak optical signals ...

American Chemical Society2014

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Walliserdeutsch is a Swiss German dialect spoken in the south west of Switzerland. To investigate the potential of automatic speech processing of Walliserdeutsch, a small database was collected based mainly on broadcast news from a local radio station. Exp ...

2014

This paper presents a method for verb phrase (VP) alignment in an English/French parallel corpus and its use for improving statistical machine translation (SMT) of verb tenses. The method starts from automatic word alignment performed with GIZA++, and reli ...

2014