Catalytic Asymmetric Reactions in Organic Chemistry

This lecture covers catalytic asymmetric reactions in organic chemistry, focusing on metal ligand dual activation. Topics include Noyori hydrogenation, modifications, new catalyst precursors, base-free protocols, ketene activation, and enamine/metal catalysis. The mechanisms proposed by Noyori and Lectka are discussed, along with the addition of imines on carbenes. The lecture also explores the direct aldol reaction, trost's direct aldol reaction with bis-Zn catalysts, and desymmetrization of diols. Various catalysts and their mechanisms are presented, such as LLB catalyst for the direct aldol reaction and chiral cobalt complexes as anion catalysts.