Concept

Ex vivo

Related publications (103)

Arrays of EAP micro-actuators for single-cell stretching applications

Mechanical stimuli are critical for the development and maintenance of most tissues such as muscles, cartilage, bones and blood vessels. The commercially available cell culture systems replicating the in vivo environment are typically based on simple membr ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010

Quantitative study of synthetic Hox transcription factor-DNA interactions in live cells

Transcription factor-DNA interactions are life sustaining and therefore the subject of intensive research. In spite of vast effort, quantitative in vivo studies of the molecular mechanisms underlying these fundamental interactions remain challenging. In th ...

2010

In vitro and in vivo studies of new photoluminescent oxygen sensors for non-invasive intravascular pO 2 measurements

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska

The concentration of oxygen and its rate of consumption are important factors playing a role in PDT and radiotherapy. One of the methods for measuring the tissular oxygen partial pressure (pO 2) is based on the use of luminophores presenting an oxygen-depe ...

2009

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Springer Verlag2009

Molecular selective interface for an implantable glucose sensor based on the viscosity variation of a sensitive fluid containing dextran and Concanavalin A

Antoine Barraud

Diabetes mellitus is a globally growing disease with more than 180 million cases worldwide and no cure exists. In order to minimize the many medical complications, tight glucose monitoring has been shown to be the best alternative. Many diabetics require i ...

EPFL2009

Ruthenium(II) Arene Compounds as Versatile Anticancer Agents

Anna Katherine Renfrew

Ruthenium-based compounds are an attractive alternative to clinically used platinum drugs due to several features including a wide range of accessible oxidation states, varied synthetic chemistry and typically lower general toxicities. One series of ruthen ...

2009

Initial In Vivo Studies with a Polymer-based MR-compatible Guide Wire

The purpose of this study was to evaluate a new polymer-based and magnetic resonance (MR) imaging-compatible guide wire for its application in MR-guided endovascular interventions, particularly for interventional peripheral MR angiography in swine experime ...

Elsevier2009

Orthopedic implant used as drug delivery system: clinical situation and state of the research

Dominique Pioletti, Vincent Stadelmann

A partial review is proposed on the existing literature for the research performed in orthopedic implant used as drug delivery system. In the first part an evaluation is given on the clinical need to deliver a drug in the surrounding of an implant. Secondl ...

2008

Microfluidics-Generated Immobilized Biomolecule Gradients on Hydrogels

Steffen Cosson

Extracellular matrix (ECM)-tethered morphogen gradients play an important role in tissue development and regeneration. There is currently a limited set of model systems that can mimic these gradients in an artificial ECM-like environment. Microfluidics off ...

2008

Principles of operation of a DNP prepolarizer coupled to a rodent MRI scanner

Rolf Gruetter, Arnaud Comment, Sami Jannin, Jacques Van Der Klink, Fiodar Kurdzesau

A dynamic nuclear polarization prepolarizer was developed and coupled to a 9.4 T rodent magnetic resonance imaging scanner in order to perform in vivo hyperpolarization experiments. In the present paper, emphasis is put on methods and hardware performance ...

2008

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