Concept

Body plan

Related publications (38)

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Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

Denis Duboule

The tetrapod vertebral column has become increasingly complex during evolution as an adaptation to a terrestrial life. At the same time, the evolution of the vertebral formula became subject to developmental constraints acting on the size of the cervical a ...

Elsevier2015

Different flavors of Toll guide olfaction

Bruno Lemaitre

Toll-like receptors are historically linked to immunity across animal phyla, but accumulating evidence suggests they play additional roles in neuronal networks and in cell-cell interactions. Ward and colleagues now identify Toll-6 and Toll-7 as instructive ...

Elsevier2015

Structure, function and evolution of topologically associating domains (TADs) at HOX loci

Denis Duboule, Nicolas Lonfat

Hox genes encode transcription factors necessary for patterning the major developing anterior to posterior embryonic axis. In addition, during vertebrate evolution, various subsets of this gene family were co-opted along with the emergence of novel body st ...

Elsevier2015

Evaluation of an active optical system for lower limb motion tracking

Hannes Bleuler, Mohamed Bouri, Jeremy Olivier, Amalric Louis Ortlieb

Observation of lower limb kinematics is essential for the characterization of gait and related activities disorders. Robust, flexible and easy to use measurement systems are precious for patients’ follow-up in different medical domains. This study aims to ...

2014

The search for a common developmental genetic mechanism of body segmentation appears to become more difficult, and more interesting, as new segmented organisms are added to the roster. Recent work in this journal by Brena and Akam on segmentation of the ge ...

2013

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

Didier Trono, Denis Duboule, Marion Leleu, Daniël Noordermeer, Guillaume Andrey

Hox genes are major determinants of the animal body plan, where they organize structures along both the trunk and appendicular axes. During mouse limb development, Hoxd genes are transcribed in two waves: early on, when the arm and forearm are specified, a ...

Amer Assoc Advancement Science2013

During development, a properly coordinated expression of Hox genes, within their different genomic clusters is critical for patterning the body plans of many animals with a bilateral symmetry. The fascinating correspondence between the topological organiza ...

Royal Soc2013

The vertebrate body plan is characterized by an increased complexity relative to that of all other chordates and large-scale gene amplifications have been associated with key morphological innovations leading to their remarkable evolutionary success. Here, ...

Academic Press Inc Elsevier Science2013

Anatomically plausible illusory posture affects mental rotation of body parts

Olaf Blanke, Silvio Ionta, Anna Sforza, Mariko Funato

During mental rotation (MR) of body parts, people internally simulate the movement of their corresponding body segments. These sensory-motor mechanisms render MR sensitive to proprioceptive information (e.g., posture). Similar mechanisms can alter illusory ...

Springer2013

The Kruppel-associated Box Repressor Domain Can Induce Reversible Heterochromatization of a Mouse Locus in Vivo

Didier Trono, Isabelle Barde, Sonia Verp, Sandra Eloise Kjeldsen, Anna Claire Groner

The study of chromatin and its regulators is key to understanding and manipulating transcription. We previously exploited the Krüppel-associated box (KRAB) transcriptional repressor domain, present in hundreds of vertebrate-specific zinc finger proteins, t ...

2012