Publications related to Broad-spectrum antibiotic

Combination of fluorescence microscopy and nanomotion detection to characterize bacteria

Giovanni Dietler, Sandor Kasas, Giovanni Longo, Justin Terence Notz Pekkanen

Antibiotic-resistant pathogens are a major health concern in everyday clinical practice. Because their detection by conventional microbial techniques requires minimally 24h, some of us have recently introduced a nanomechanical sensor, which can reveal moti ...

Wiley-Blackwell2013

Temporal variability of antibiotics fluxes in wastewater and contribution from hospitals

David Andrew Barry, Luca Rossi, Sylvain Coutu

Significant quantities of antibiotics are used in all parts of the globe to treat diseases with bacterial origins. After ingestion, antibiotics are excreted by the patient and transmitted in due course to the aquatic environment. This study examined tempor ...

Public Library of Science2013

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

Jieping Zhu

The design, synthesis and antibiotic activities of the modified carboxylate binding pocket (D-O-E ring) of vancomycin (1) were summarized in this short account. The preliminary Structure-Activity Relationship (SAR) studies indicated that both the structure ...

Schweizerische Chemische Gesellschaft2013

Aqueous Oxidation of Sulfonamide Antibiotics: Aromatic Nucleophilic Substitution of an Aniline Radical Cation

Jeremy Samuel Arey, Peter Rudolf Tentscher

Sulfonamide antibiotics are an important class of organic micropollutants in the aquatic environment. For several, sulfur dioxide extrusion products have been previously reported upon photochemical or dark oxidation. Using quantum chemical modeling calcula ...

2013

Polycyclic Peptide Therapeutics

Christian Heinis, Vanessa Baeriswyl

Owing to their excellent binding properties, high stability, and low off-target toxicity, polycyclic peptides are an attractive molecule format for the development of therapeutics. Currently, only a handful of polycyclic peptides are used in the clinic; ex ...

Wiley-V C H Verlag Gmbh2013

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Tamar Kohn, Florence Bonvin, Julien Omlin, Rebecca Rutler, Timothy Strathmann

The presence of potentially persistent and bioactive human metabolites in surface waters gives rise to concern; yet little is known to date about the environmental fate of these compounds. This work investigates the direct photolysis of human metabolites o ...

Amer Chemical Soc2013

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE

Bruno Lemaitre

The Drosophila antimicrobial response is one of the best characterized systems of pattern recognition receptor-mediated defense in metazoans. Drosophila senses Gram-negative bacteria via two peptidoglycan recognition proteins (PGRPs), membrane-bound PGRP-L ...

Amer Assoc Immunologists2012

Fully Integrated Biochip Platforms for Advanced Healthcare

Giovanni De Micheli, Sandro Carrara, Catherine Dehollain, Jacopo Olivo, Irene Taurino, Andrea Cavallini, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh, Wayne Burleson

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring ...

Mdpi Ag2012

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Broad-spectrum antibiotic

Combination of fluorescence microscopy and nanomotion detection to characterize bacteria

Temporal variability of antibiotics fluxes in wastewater and contribution from hospitals

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

Sources, Spreading and Fate of Antibiotic Resistance Genes and Resistant Bacteria in Vidy Bay, Lake Geneva, Switzerland

Aqueous Oxidation of Sulfonamide Antibiotics: Aromatic Nucleophilic Substitution of an Aniline Radical Cation

Polycyclic Peptide Therapeutics

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Single-Cell Analysis of Mycobacterial Persistence Using Microfabricated Tools

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE

Fully Integrated Biochip Platforms for Advanced Healthcare

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Chat with Graph Search

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Polycyclic Peptide Therapeutics

Aqueous Oxidation of Sulfonamide Antibiotics: Aromatic Nucleophilic Substitution of an Aniline Radical Cation

Sources, Spreading and Fate of Antibiotic Resistance Genes and Resistant Bacteria in Vidy Bay, Lake Geneva, Switzerland

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

Combination of fluorescence microscopy and nanomotion detection to characterize bacteria

Single-Cell Analysis of Mycobacterial Persistence Using Microfabricated Tools

Fully Integrated Biochip Platforms for Advanced Healthcare

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE

Temporal variability of antibiotics fluxes in wastewater and contribution from hospitals