Explores Chemical Biology's interdisciplinary nature, enzyme inhibition, genetic methods, and metabolic regulation, highlighting its real-world relevance through recent Nobel Prize contributions.
Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
Explores kinase inhibitors, their types, mechanisms, and experimental evaluation, emphasizing the significance of covalent drugs in modern pharmaceutical research.
Explores enzyme inhibition mechanisms, including competitive, uncompetitive, and mixed inhibition, as well as autocatalysis and their impact on enzyme kinetics.