Cloud condensation nuclei (CCNs), also known as cloud seeds, are small particles typically 0.2 μm, or one hundredth the size of a cloud droplet. CCNs are a unique subset of aerosols in the atmosphere on which water vapour condenses. This can affect the radiative properties of clouds and the overall atmosphere. Water requires a non-gaseous surface to make the transition from a vapour to a liquid; this process is called condensation. In the atmosphere of Earth, this surface presents itself as tiny solid or liquid particles called CCNs. When no CCNs are present, water vapour can be supercooled at about for 5–6 hours before droplets spontaneously form. This is the basis of the cloud chamber for detecting subatomic particles. The concept of CCN is used in cloud seeding, which tries to encourage rainfall by seeding the air with condensation nuclei. It has further been suggested that creating such nuclei could be used for marine cloud brightening, a climate engineering technique. Some natural environmental phenomena, such as the one proposed in the CLAW hypothesis also arise from the interaction between naturally produced CCNs and cloud formation. A typical raindrop is about 2 mm in diameter, a typical cloud droplet is on the order of 0.02 mm, and a typical cloud condensation nucleus (aerosol) is on the order of 0.0001 mm or 0.1 μm or greater in diameter. The number of cloud condensation nuclei in the air can be measured at ranges between around 100 to 1000 per cm3. The total mass of CCNs injected into the atmosphere has been estimated at 2e12kg over a year's time. There are many different types of atmospheric particulates that can act as CCN. The particles may be composed of dust or clay, soot or black carbon from grassland or forest fires, sea salt from ocean wave spray, soot from factory smokestacks or internal combustion engines, sulfate from volcanic activity, phytoplankton or the oxidation of sulfur dioxide and secondary organic matter formed by the oxidation of volatile organic compounds.

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